DNA Synthesis Market size was USD 4.7 billion in 2024 and is estimated to reach USD 45.6 billion by the end of 2037, expanding at a CAGR of 19.1% during the forecast period, i.e., 2025-2037. In 2025, the industry size of DNA synthesis is evaluated at USD 5.6 billion.
DNA synthesis plays a vital role in the production of personalized medicine, particularly in gene therapy and oncology. Customized or personalized medications are formulated considering factors such as lifestyle and genetic makeup. In most chronic disorder cases such as cancer, the one-fits-all treatment approach does not work and increases the demand for personalized medicines. Researchers through DNA sequencing of tumor cells identify mutations or alterations that lead to cancer progression and further through DNA synthesis they create specific gene constructs or proteins that target the mutations directly, reduce their growth, and offer better treatment results. The increasing cases of chronic disorders such as cancer are augmenting the high demand for synthetic DNA solutions.
Key players in the DNA synthesis market are raising funds to enhance their research capabilities and aid researchers to drive their full potential to develop advanced solutions. For instance, in April 2023, ANSA Biotechnologies revealed that the company raised USD 68 million in Series A Funding to enhance DNA synthesis. This funding is aiding the company in advancing next-gen technology platforms, expanding production and R&D facilities, increasing multidisciplinary teams, and introducing DNA synthesis services.
Growth Drivers
Challenges
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Base Year |
2024 |
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Forecast Year |
2025-2037 |
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CAGR |
19.1% |
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Base Year Market Size (2024) |
USD 4.7 billion |
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Forecast Year Market Size (2037) |
USD 45.6 billion |
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Regional Scope |
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By Service (Oligonucleotide Synthesis, Gene Synthesis)
The oligonucleotide synthesis segment is anticipated to account for DNA synthesis market share of around 56.5% by 2037. The segment is further classified into standard oligonucleotide synthesis and custom oligonucleotide synthesis. The ongoing advancements in oligonucleotide synthesis are anticipated to boost their applications in genomic sequencing, molecular diagnosis, and synthetic biology. Also, the rise in research activities in the above-mentioned fields augments a high demand for custom-synthesized oligonucleotides. Universities, research institutes, and biotech labs widely rely on these oligonucleotides due to their high precision and accuracy.
By Application (Research & Development, Diagnostics, Therapeutics)
The oligonucleotide synthesis segment is anticipated to account for DNA synthesis market share of around 56.5% by 2037. The research and development activities help to improve the DNA synthesis techniques and explore new application areas. The increasing investments by end use organizations such as biotechnology and pharmaceutical, universities, and market players to enhance and expand their research and development capabilities are contributing to the segmental growth.
DNA synthesis technology manufacturers are also raising funds to strengthen their R&D facilities and operations. For instance, in April 2023, NunaBio a TechBio producer of synthetic DNA for chemical research announced that it raised USD 2.5 million in seed funding to expand and accelerate its R&D infrastructure and activities. The funding was supported by the European Regional Development Fund and managed by Northstar Ventures, Pioneer Group, Ascension Life Fund, and Martlet Capital.
Our in-depth analysis of the DNA synthesis market includes the following segments:
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Service |
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Method |
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Application |
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End use |
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North America Market Forecast
North America DNA synthesis market is likely to dominate revenue share of over 37.1% by 2037. The strong presence of research organizations and biopharma companies is augmenting the demand for DNA synthesis technologies. The rising prevalence of genetic and chronic disorders and the quick adoption of personalized medications are also contributing to DNA synthesis solution sales growth.
In the U.S., the increasing investments by government and non-government organizations in genomics and biotechnology are pushing the sales of DNA synthesis solutions. The National Institutes of Health (NIH) is one of the major contributors to the genomic programs that contribute to DNA synthesis market growth in the U.S. For instance, in April 2024, the National Institutes of Health (NIH) awarded USD 27 million to establish a new network of genomics-enabled learning health systems in the country.
In Canada, the presence of advanced healthcare facilities and national healthcare platforms for genome sequencing and analysis such as Canadian Genomics Enterprise is significantly contributing to the demand for DNA synthesis solutions. The quick adoption of new and personalized diagnosis and treatment plans for genetic diseases also drives the sales of synthesized DNA solutions.
Europe Market Statistics
By 2037, Europe DNA synthesis market is projected to capture over 23.3% revenue share owing to the high activities in drug discovery and development. The advancements in biotechnology and life science sectors are generating lucrative opportunities for DNA synthesis solution producers in the region.
In the U.K., well-known universities including Oxford and Cambridge constantly collaborate with biotech firms for research in genomics, drug discovery, and synthetic biotechnology, which contributes to DNA synthesis technologies. For instance, in October 2023, Evonetix announced that it successfully installed its first DNA synthesis development platform at the Imperial College London to optimize research in gene synthesis. Such strategic moves between institutions and industry giants are positively influencing the overall DNA synthesis market growth.
The swift integration of precision medicines into clinical practices, which relies highly on custom DNA synthesis is uplifting Germany’s market position in Europe. The genomDE strategy of the country that aims to enhance the adoption of genomic medicines is fueling the use of DNA synthesis solutions in drug development and gene therapies.
Key players in the DNA synthesis market are investing heavily in research and development activities to enhance their product offerings. They are also forming strategic partnerships with other players and collaborating with research organizations to develop innovative DNA synthesis solutions. Furthermore, industry giants are employing acquisition and merger strategies to expand their presence in the DNA synthesis market. Regional expansion tactics are aiding them to tap into high-potential markets to cater to a wider consumer base.
Some of the key players include:
Author Credits: Radhika Pawar
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