Potassium-Sparing Diuretics Market Trends

Growth Drivers

• Higher Rates of Obesity Among Adults - There are approximately 1 in 11 adults (9.2%) who have severe obesity in the United States. There is a greater proportion of overweight men (34.1%) than overweight women (27.5%). With an increase in obesity, there is an increase in the risk of developing high blood pressure and heart disease which results in an increase in the need for medications like potassium-sparing diuretics. These medications work to lower the levels of sodium and water in the body, which can help reduce the risk of associated health problems.
• Huge Number of People Suffering from Chronic Diseases - According to estimates, 6 out of 10 Americans have a chronic disease. There are about 40 million Americans who are limited in their normal activities owing to chronic health issues. Potassium-sparing diuretics are medications used to treat high blood pressure, fluid retention, and other conditions caused by water retention. Their use is increasing owing to the rising prevalence of chronic diseases such as diabetes, hypertension, and heart failure, which increase the risk of fluid retention.
• A Growing Awareness Of Edema And Pulmonary Edema Prevalence - The prevalence of pulmonary edema among patients with heart failure is estimated to be 75000-83,000 cases per 100,000 individuals worldwide. Edema is swelling in the body caused by excess fluid trapped within the tissues. As more people become aware of edema, they are increasingly seeking treatments, such as diuretics, to reduce the excess fluid. Doctors are also becoming more aware of the condition, leading to earlier detection and better treatments.
• Increasing Incidence of Cirrhosis Among Adults - Cirrhosis is a chronic liver disease which is characterized by fibrosis and the formation of scar tissue. This causes the liver to not be able to function properly and can lead to a buildup of potassium in the body, which can be dangerous. Potassium-sparing diuretics help to flush out the excess potassium and can help to reduce the symptoms of cirrhosis. It is estimated that about one in four hundred adults in the United States have cirrhosis. The prevalence of cirrhosis is higher in adults between the ages of 45 and 54. Cirrhosis affects about one in every 200 Americans aged 45 to 54.
• A Rise In The Number Of Heart Failure Cases - The Centers for Disease Control and Prevention estimates that approximately 6.2 million Americans have heart failure. According to death certificates, heart failure contributed to 379,800 deaths in 2018 (13.4%). Potassium-sparing diuretics are used to treat congestive heart failure and other cardiac-related conditions as they help the body to eliminate excess fluid and sodium while preserving potassium. This helps to reduce the strain on the heart, which in turn can help to improve symptoms and increase quality of life.

Challenges

• Availability of generic alternatives - Generic drugs tend to be significantly cheaper than their brand-name counterparts, and since potassium-sparing diuretics are already relatively inexpensive, the presence of generics reduces the incentive for people to purchase the more expensive brand-name drugs. This results in a decrease in market growth for potassium-sparing diuretics.
• High cost of potassium-sparing diuretics
• Stringent regulations imposed by governments to control the usage of these drugs