Vitiligo Treatment Market size was estimated at USD 624.9 million in 2024 and is expected to surpass USD 1.17 billion by the end of 2037, rising at a CAGR of 5% during the forecast period, i.e., 2025-2037. In 2025, the industry size of vitiligo treatment is assessed at USD 656.1 million.
Technological developments are significantly boosting the growth of the vitiligo treatment market, by presenting innovative therapies that improve accessibility and efficacy. Traditional treatments such as light therapy, corticosteroid creams, and skin grafting usually present limitations such as side effects, inconsistent outcomes, and high costs. Technological advancements in regenerative medicine, biologics, and gene therapies are expanding treatment options while addressing the growing demand for more effective and safer solutions.
Technological development of Janus Kinase (JAK) inhibitors which have shown some positive results in restoring pigmentation for vitiligo patients. For instance, in September 2021, the U.S. Food and Drug Administration (FDA) approved ruxolitinib (Opzelura) cream 1.5% for the treatment of nonsegmental vitiligo in patients aged 12 and older. This tropical JAK inhibitor works by inhibiting pathways that lead to immune system attacks on melanocytes, the cells that are responsible for pigmentation. Such targeted therapies are shifting the vitiligo treatment market by addressing the underlying causes of vitiligo rather than merely managing symptoms.
Growth Drivers
Challenges
Base Year |
2024 |
Forecast Year |
2025-2037 |
CAGR |
5% |
Base Year Market Size (2024) |
USD 624.9 million |
Forecast Year Market Size (2037) |
USD 1.17 billion |
Regional Scope |
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Type (Segmental Vitiligo, Non-Segmental Vitiligo)
The non-segmental vitiligo segment is predicted to have a significant vitiligo treatment market share during the forecast period of 2025-2037. This dominance is due to the increase in patients diagnosed with non-segmental vitiligo, worldwide. When the skin color starts fading, the most common kind of vitiligo causes skin patches to arise all over the body. Non-segmental vitiligo is generally present when white spots on a person's body are symmetrical apart from asymmetrical. Nevertheless, therapies for non-segmental vitiligo may differ significantly depending on the patient's preferences and the severity of their disease. As a result, the increase in awareness about vitiligo symptoms, causes, and improved treatment alternatives provide lucrative growth opportunities for the segment.
For example, in April 2023, Incyte announced the European Commission (EC) approval of opzelura (ruxolitinib) cream for the treatment of non-segmental vitiligo with facial involvement in adults and adolescents. Opzelura is the first and only permitted treatment in the European Union (EU) to provide support for repigmentation in eligible patients with non-segmental vitiligo, a chronic autoimmune disease featuring depigmentation of skin and decreased quality of life.
Treatment Type (Topical Treatment, Light Therapy, Surgical Procedures, Others)
Topical treatment segment is anticipated to dominate around 49.5% vitiligo treatment market share by the end of 2037. Topical treatments such as calcineurin inhibitors, corticosteroids, and many new options similar to Janus kinase (JAK) inhibitors are preferred due to their ease of affordability, application, and non-invasive nature. These treatments are mainly effective in managing decreasing inflammation, localized vertigo, and promoting repigmentation while making them a unique choice among patients and healthcare providers.
For instance, according to Vitiligo Research Foundation, in September 2024, Aclaris Therapeutics' lead drug applicant ATI-50002 Topical Solution 0.46% for vitiligo is a JAK1/JAK3 inhibitor. Phase II clinical trials were completed in 2020 with no further development. In January 2024 company declared top-line results from its Phase 2b study of ATI-1777, an investigational topical soft JAK 1/3 inhibitor, in patients with mild to severe atopic dermatitis, with an eye for vitiligo down the road.
Our in-depth analysis of the global vitiligo treatment market includes the following segments:
Type |
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Drug Class Type |
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Treatment Type |
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Distribution Channel |
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End user |
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North America Market Analysis
North America in vitiligo treatment market is likely to account for around 40.8% revenue share by 2037, owing to developed healthcare infrastructure, significant investment in research and development, and rising awareness levels. Increasing healthcare spending, coupled with the presence of key market players, is further propelling market growth. The U.S. and Canada are projected to contribute the major share of the North America vitiligo treatment market.
The increasing prevalence of vitiligo in the United States, the emerging healthcare industry, the growing adoption of modern technologies, and rising innovative surgery procedures by key players are the factors driving the U.S. market throughout the forecast period. According to the American Academy of Dermatology (AAD), in June 2022, vitiligo affects around one in four persons in the U.S. This huge vitiligo patient pool, along with growing demand for enhanced therapeutic approaches, is driving up demand for the market in the region.
Canada is experiencing growth in the vitiligo treatment market due to advancements in treatment options, increasing awareness, and a supportive healthcare system. For instance, in October 2024, Incyte Biosciences Canada declared that Health Canada has approved a Notice of Compliance for OPZELURA (ruxolitinib (as ruxolitinib phosphate)) cream 1.5%, a non-steroidal topical JAK inhibitor, for the topical treatment of mild to moderate atopic dermatitis in adult and pediatric patients 12 years of age and more whose disease is not effectively controlled with conventional topical prescription therapies or when those therapies are not advisable.
Asia Pacific Market Analysis
Asia Pacific is expected to experience significant growth during the forecast period due to rising awareness of skin disorders, increasing patient population, and growing healthcare expenditure. The countries in the Asia Pacific dealing with vitiligo have resulted in the demand for improved treatment alternatives for vitiligo. The rise in knowledge of vitiligo, as well as initiatives to minimalize related stigma, are encouraging more people to seek treatment in the Asia Pacific. Moreover, the rising prevalence of vitiligo and the increasing demand for cosmetic and dermatological treatments are important drivers.
The China vitiligo treatment market is witnessing prominent growth in the country owing to the ongoing research and development activities and innovations in the available treatments to cater to the rising vitiligo cases. In September 2023, Huahai Institute of Vitiligo Research expanded its operations in Shanghai, to bring TCM-based vitiligo treatment to local patients, thus, improving accessibility to high-caliber traditional Chinese medicines. Furthermore, in April 2024, China Medical System Holdings Limited and Incyte entered into a partnership and license agreement to develop and commercialize povorcitinib in Mainland China, Macao, Hong Kong, and Taiwan.
Japan has a significantly high demand for dermatological and cosmetic treatments. Also, the penetration of global players in the country has improved vitiligo treatments. In 2023, Merck initiated the clinical trial for MK-6194 in several countries including Japan, catering to non-segmental vitiligo patients.
The competitive landscape of the vitiligo treatment market is well-defined by dynamic innovation and strategic activities targeted at meeting the unmet necessities of a wide range of patients. A robust emphasis on research and development is noticeable, with several businesses investing in new therapies and treatment modalities such as light therapy, topical treatments, and surgical possibilities. Here are some leading players in the vitiligo treatment market:
Author Credits: Radhika Pawar
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