Global Vitamin K2 Market Size, Forecast, and Trend Highlights Over 2025-2037
Vitamin K2 Market size is projected to grow from USD 705.6 million in 2024 to USD 14.22 billion, witnessing a CAGR of over 25.7% CAGR during the forecast period i.e., between 2025 and 2037. In 2025, the industry size of vitamin K2 is evaluated at USD 851.8 million.
The market's growth can be ascribed to the increasing number of patients suffering from vitamin K2 deficiency. This deficiency can lead to bleeding, osteoporosis, poor bone development and high risk of cardiovascular diseases. According to a report by the National Library of Medicine, vitamin K deficiency bleeding deficiency can occur in 0.25 to 1.7% of infants. Doctors often prescribe vitamin k2 supplements to pregnant women to avoid postpartum hemorrhage. According to the National Institutes of Health in 2023, out of 76.7 million delivery hospitalizations, 2.3 million were complicated by postpartum hemorrhage. The report further says that vitamin K supplementation for pregnant women provides remarkable benefits to both neonatal and maternal outcomes.
Besides this, vitamin K2 is a multifunctional micronutrient implicated in age-related diseases such as cardiovascular ailments and significant bleeding. According to data published by AARP in April 2021, about two-thirds of men over age 70 don’t get enough vitamin K2 in the U.S. Doctors are increasingly prescribing vitamin K2 to the old age population to keep bones healthy and prevent muscle weakness.
Vitamin K2 Sector: Growth Drivers and Challenges
Growth Drivers
- Increase in cases of osteoporosis: Epidemiological studies suggest that vitamin K2 deficiency is related to osteoporosis. According to the International Osteoporosis Foundation, currently, 1 in 3 women and 1 in 5 men over the age of 50 globally, are suffering from bone diseases, such as osteoporosis. The daily recommended vitamin K2 intake for adult women is 90 mcg, however, higher doses may be required for optimal bone health. The rising cases of osteoporosis are augmenting the market expansion in the assessed period.
- Rising heart disease: Vitamin K2 helps reduce the risk of heart disease by regulating calcium homeostasis. Doctors are emphasizing on intake of vitamin K2 to increase cardiac output and decrease blood lactate. According to the National Institutes of Health, cardiovascular diseases are the leading cause of mortality. The report further states that in 2022, 702,880 people died from heart disease, which is equivalent to 1 in every 5 deaths.
- Efficient in fighting against cancer: Various studies suggest that vitamin K2 has been shown significant anticancer activities. It has been found to induce apoptosis in the cells of cancer. According to the World Health Organization, in 2022, there were an estimated 20 million new cancer cases and 9.7 million deaths. Due to the therapeutic effects of taking vitamin K on cancer, the demand for vitamin K in the form of powder or oil is rising globally.
Challenges
- Issues related to expiry dates: Medicines and supplements have a shelf life of almost 2 years. If the supplement is not being consumed in a certain period, then it becomes hazardous for health which can cause serious health problems in the future. This factor is expected to prompt the consumer to buy less vitamin K2 for consumption.
Vitamin K2 Market: Key Insights
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Base Year |
2024 |
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Forecast Year |
2025-2037 |
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CAGR |
25.7% |
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Base Year Market Size (2024) |
USD 705.6 million |
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Forecast Year Market Size (2037) |
USD 14.22 billion |
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Regional Scope |
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Vitamin K2 Segmentation
Application (Nutraceutical, Food, Pharmaceuticals)
The nutraceuticals segment is anticipated to hold the largest vitamin K2 market size by the end of 2037 attributed to the surge in the number of people who are taking dietary supplements in the form of nutraceuticals. For instance, according to Penn State Health News in May 2024, almost 59 million Americans use some type of supplements. Additionally, there is a rise in research and development in the supplements and nutraceuticals domain. A study by the National Institutes of Health in 2021 stated that research in the field has grown with over 70,000 published articles.
Source (Natural, Synthetic)
The natural segment is projected to witness significant vitamin K2 market size in the coming decade. Various market players are making supplements of superior quality for supporting bone and heart health. For instance, in 2021, Gnosis by Lesaffre, declared the launch of a new version of vitaMK7 natural vitamin K2 with enhanced protection. The product ensures the stability of menaquinone ingredients in complex finished product formulations.
Our in-depth analysis of the vitamin K2 market includes the following segments:
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Type |
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Application |
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Source |
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Customize this ReportVitamin K2 Industry - Regional Synopsis
North America Market
The North America vitamin K2 market is projected to hold the largest market share by the end of 2037. The growth can be attributed to the increasing focus of consumers on health. According to the Centers for Disease Control and Prevention in 2024, early and classical VKDB is more common, occurring in 1 in 60 to 1 in 250 newborns, in the U.S. New babies are given vitamin K2 injections to prevent a serious disease called hemorrhagic disease. The factors are propelling the market growth in the region and creating lucrative opportunities. In Canada, there is a surge in cases of osteoporosis leading to increased demand for vitamin K2 supplements. According to data published by Amgen Canada in 2022, at least 1 in 3 women and 1 in 5 men will break a bone due to osteoporosis in their lifetime.
Asia Pacific Market
Rising cases of heart-related problems are projected to give thrust to the market expansion. According to data published by the World Health Organization in 2023, cardiovascular diseases account for 3.9 million deaths in the South East Asia region every year. Doctors prescribe to take vitamin K2 to reduce arterial stiffness and slow down the progression of vascular and valvular calcification. Other than this, according to the International Osteoporosis Foundation, it is projected that more than 50% of all osteoporotic hip fractures will occur in Asia by 2050. Women are taking vitamin K2 to prevent fractures in the postmenopausal period.
According to the International Trade Administration in April 2021, Japan is the world’s 3rd largest dietary supplements market. A rapidly aging population and a surge in health consciousness are boosting the sector’s growth. Additionally, according to the International Osteoporosis Foundation in June 2022, an estimated 13 million people are living with osteoporosis in Japan and 240,000 patients experience hip fractures. In Japan and other parts of Asia, vitamin K2 is used as a treatment for osteoporosis. National Institutes of Health states that Vitamin K2 is considered vital in providing standard care in Japan and suggests that its supplementation improves lumbar bone mineral density and reduces undercarboxylated osteocalcin.
Companies Dominating the Vitamin K2 Landscape
- Kappa Bioscience Group
- Company Overview
- Business Strategy
- Key Product Offerings
- Financial Performance
- Key Performance Indicators
- Risk Analysis
- Recent Development
- Regional Presence
- SWOT Analysis
- Gnosis by Lesaffre
- Koninklijke DSM N.V
- Pfizer Inc.
- Viridis BioPharma Pvt. Ltd.
- DuPont de Nemours, Inc.
- Seebio Biotech (Shanghai) Co., Ltd.
- GeneFerm Biotechnology Co., Ltd.
- Kyowa Hakka Bio Co., Ltd.
- International Flavors & Fragrances Inc.
The competitive landscape of the Vitamin K2 market is rapidly evolving as established key players and new entrants are investing in launching quality supplements. Key players in the market are focused on developing new technologies and products catering to the stringent regulatory norms and consumer demand. These key players are adopting several strategies such as mergers and acquisitions, joint ventures, partnerships, and novel product launches to enhance their product base and strengthen their market position. Here are some key players operating in the global market:
In the News
- In February 2024, the International Life Sciences Institute established a task force aimed to advance and explore the understanding of the health benefits of vitamin K2. The study is to provide evidence-based insights to enhance public awareness. The task force includes experts from companies such as DSM-Firmenich, Novonesis, Lesaffre, etc.
- In May 2021, Gnosis by Lesaffre announced that it is wide-spreading its capabilities as a global supplier of vitamin K2 with its acquisition of NattoPharma.
Author Credits: Radhika Pawar
- Report ID: 4278
- Published Date: Feb 21, 2025
- Report Format: PDF, PPT
