Topical Pain Relief Market Trends

  • Report ID: 2473
  • Published Date: May 21, 2025
  • Report Format: PDF, PPT

Topical Pain Relief Sector: Growth Drivers and Challenges

Growth Drivers

  • Affordable healthcare interventions: One of the exceptional drivers for the topical pain relief market is the introduction of cost-effective treatment measures and improvements in medical care. This is inspiring healthcare facilities to opt for non-opioid management strategies due to their strong efficacy in pain management. In this context, a clinical study by AHRQ in 2022 reported that early interference with these pain relief therapies significantly reduced hospitalizations for musculoskeletal pain by 12.3%, which conserved approximately USD 1.5 billion in the U.S. medical expenditure in a span of 2 years. Hence, a positive outlook for market growth with such measures.

  • Increasing partnerships & launch activities: Another significant driver for the topical pain relief market is the increasing launch activities by the global players to capture maximum market share. For instance, in 2024, Pfizer Inc. declared a partnership with Walgreens, aiming to expand its OTC pain relief access with a market share of 15.6%, thereby supporting the demand for topical pain relief medications. Furthermore, in 2023, GSK Plc launched a lidocaine-based patch with 30% faster absorption, with a sales value of USD 450.5 million in the first year itself. This is the evidence for a wider scope, thereby driving business in this sector.

Historical Patient Growth (2010-2020) and Its Impact on Market Expansion

The increasing global burden of chronic pain conditions among the aging population has created a strong necessity for pain relief therapeutics. This, in turn, increases the wide adaptability for non-opioid solutions such as lidocaine, capsaicin, and diclofenac-based formulations, with the support of regulatory frameworks. Besides, the opioid shortage increased the demand for safe alternatives in the U.S. and Europe, and Asia, and the rising diagnostic rates led to an increased patient pool, thus denoting a positive outlook for the topical pain relief market expansion.

Historical Patient Growth (2010-2020) in Topical Pain Relief Users (Millions)

Country

2010 Patients (M)

2020 Patients (M)

CAGR (2010-2020)

USA

25.4

38.8

4.7%

Germany

8.6

13.2

4.8%

France

7.2

10.6

4.5%

Spain

4.7

7.3

4.9%

Australia

3.5

5.6

5.1%

Japan

12.9

18.8

4.2%

India

15.7

29.3

6.8%

China

22.4

41.6

6.5%

Manufacturer Strategies Shaping the Topical Pain Relief Market

The topical pain relief market is significantly supported by the leading manufacturers, who are aiming to strengthen their ecosystem in the global market. They are unveiling the pathway to several tactical revenue opportunities with their strategic collaborations and localized production initiatives. In this regard, in 2023, Pfizer Inc. gained a 12% increase in market share, which is estimated to be USD 480.5 million, with the launch of lidocaine-menthol hybrid gel. Similarly, GSK Plc boosted its sales by 18% with a joint venture in India. Hence, these strategies positively influence the revenue growth and shape the topical pain relief sector.

Revenue Potential for Manufacturers

Strategy

Company

Revenue Impact

Hybrid Formulations

Pfizer

$480.5 million (2023)

Emerging Market JVs

GSK

$270.6 million (India, 2023)

Localized API Production

Sanofi

$210 million cost savings (2024)

Telehealth Partnerships

Johnson & Johnson

30.3% adherence boost

Premium Patches

Hisamitsu

$320.2 million (Japan, 2023)

Challenge

  • Government price controls: One of the major bottlenecks of the topical pain relief market is the price limits imposed by the governments worldwide. Besides, these price controls can hinder profitability in regions such as Europe, where there is a reduced margin of 15 to 20% for the manufacturers. For instance, in 2023, GSK Plc partnered with the Federal Joint Committee of Germany to improve its product margin. Furthermore, WHO states that this limits the pharmaceutical investment, thereby slowing down product innovations, with 60% of nations with low-income countries being enforced with price controls.

Base Year

2024

Forecast Year

2025-2037

CAGR

6.2%

Base Year Market Size (2024)

USD 12.9 billion

Forecast Year Market Size (2037)

USD 25.4 billion

Regional Scope

  • North America (U.S., and Canada)
  • Asia Pacific (Japan, China, India, Indonesia, Malaysia, Australia, South Korea, Rest of Asia Pacific)
  • Europe (UK, Germany, France, Italy, Spain, Russia, NORDIC, Rest of Europe)
  • Latin America (Mexico, Argentina, Brazil, Rest of Latin America)
  • Middle East and Africa (Israel, GCC North Africa, South Africa, Rest of the Middle East and Africa)

Browse key industry insights with market data tables & charts from the report:

Frequently Asked Questions (FAQ)

In the year 2025, the industry size of topical pain relief is assessed at USD 13.8 billion.

Topical Pain Relief Market size was valued at USD 12.9 billion in 2024 and is expected to reach USD 25.4 billion by 2037, expanding at around 6.2% CAGR during the forecast period i.e., between 2025-2037.

North America industry is set to account for largest revenue share of 40.8% by 2037.

The major players in the market are Reckitt Benckiser Group plc, Teikoku Pharma USA, Inc., Topical BioMedics, Inc., Sun Pharmaceutical Industries Ltd., AdvaCare Pharma®, Sanofi, Johnson & Johnson Services, Inc., Novartis AG,
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