Tangential Flow Filtration Market Trends

Growth Drivers

• Increasing Revenue of Cell and Gene Therapy – with gene therapy holding a promise to treat a wide range of diseases, such as heart disease, cancer, cystic fibrosis, diabetes, hemophilia, and AIDS whose ubiquity is rising worldwide, the revenue growth of these therapies depicts an upsurge. For instance, as per projections, between 2021-2026 the sales of cell and gene therapies are anticipated to rise from USD 4 billion to nearly USD 45 billion a year. Moreover, as large-scale purification of viruses and viral vectors for gene therapy applications and viral vaccines can be attained with the use of TFF, the rising investment in gene therapy is anticipated to boost market growth.
• Growing Sales of Biotech drugs and Biologics – global sales from biotechnology drugs amounted to over USD 400 billion in 2022. With the rising share of biotech drugs, the TFF market is anticipated to grow continuously as TFF is used in almost every biopharmaceutical manufacturing downstream process to provide gentle, fast concentration, and diafiltration.
• Increasing Global Burden of Diseases –As per an estimation over 877,500 Americans die every year due to heart disease or stroke, accounting for nearly one-third of all deaths. With the technological advancements in the field of biotechnology, it is anticipated that a minimum of 45% of the current global disease burden can be addressed using biological development. This, as a result, is expected to boost market growth.
• Widening Scope of Tissue Engineering and Regenerative Medicine – The expansion in the field of bioengineering as well as biomedicine can be attributed to the growing employment of bioengineers and biomedical engineers which in the United States is projected to rise nearly 10% between 2021 to 2031. This expansion is expected to boost the market growth as applications of TFF involve its use for clarification and removal of cells, as well as cellular debris from cell culture broths.

Challenges

• High capital expenditure – The rising need for huge capital investments at the initial stage of setting up new production facilities is a major restraining factor to the market growth. Owing to this the survival of small players and new entrants is found difficult, which is hampering the market growth. Moreover, the stringent regulatory policies of the government are projected to challenge the tangential flow filtration market.
• Easy availability of substitutes
• Complex & changing product requirements