Soft Tissue Allografts Market size was valued at USD 4.27 Billion in 2023 and is expected to reach USD 10.05 Billion by the end of 2036, expanding at around 6.8% CAGR during the forecast period i.e., between 2024-2036. In the year 2024, the industry size of soft tissue allografts is assessed at USD 4.53 Billion. The growth of the market can be attributed to the increasing trauma cases related to accidents, sports injuries, and others. According to the data from 2021 from the Accident Compensation Corporation (ACC), there were roughly 692 million in injury claims related to sports and recreation. Moreover, according to the National Library of Medicine, 33 million skeletal injuries occur in the United States each year, of which 50% are tendon and ligament injuries.
In addition to these, factors that are believed to fuel the market growth of soft tissue allografts include the increasing count of anterior cruciate ligament (ACL) sprains and tears. Allograft tissue is the tissue that has been surgically implanted from one person to another. Soft tissue allografts are the replacement tissues used in an anterior cruciate ligament (ACL) to repair the damaged ligament, torn menisci, osteochondral defects, and spinal surgery. Utilization of allografts for soft tissue reconstruction results in less donor tissue site mortality and relatively short surgical time. For instance, in the United States, the prevalence rate of ACL sprains and tears ranges from 110,000 to 226,000 per year.
Growth Drivers
Growing Incidences of Sports Injuries - Sports injuries happen when exercising or playing a sport. These injuries affect the bones, muscles, tendons, ligaments, and other body structures. As per a report, in the United States, every year, approximately 4 million kids aged 14 and under suffer injuries while playing sports or engaging in leisure activities.
Rising Prevalence of Osteoarthritis - Older people have a higher risk to develop osteoarthritis. The breakdown of cartilage, a stretchy material that reduces the friction in joints, causes primary osteoarthritis. For instance, around 3 to 6% of people worldwide suffer from osteoarthritis. It is a cause of moderate to severe impairment in nearly 44 million people.
Increase in Trauma Cases – As per the World Health Organization, every year, approximately 1.3 million people's lives are ended prematurely as an outcome of a road accident. Non-fatal injuries affect between 20 and 50 million people who have become disabled as a consequence of their injury. These injuries many times cause wear and tear of bones and muscles, breaking the stability of the skeletal system.
Upsurge in Musculoskeletal Diseases - The musculoskeletal issues can affect the muscles, bones, and joints. The severity of MSDs can vary. In some cases, they cause pain and discomfort and in severe situations, it can lead to allografting. Musculoskeletal issues entail a variety of problems, including tendinitis, carpel tunnel syndrome, and fibromyalgia. Nearly 1.71 billion people around the world have musculoskeletal diseases
Technological Advancement in Allografts - The newest technology from the CYGNUS family of amniotic tissue allografts, CYGNUS Matrix Disks, was just released, by Vivex Biologics, Inc. With enhanced handling and increased workability, CYGNUS® Matrix Disks are a flexible, multi-layer allograft that preserves the amnion layer
Challenges
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Base Year |
2023 |
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Forecast Year |
2024-2036 |
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CAGR |
6.8% |
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Base Year Market Size (2023) |
USD 4.27 Billion |
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Forecast Year Market Size (2036) |
USD 10.05 Billion |
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Regional Scope |
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Application (Orthopedic, Dentistry, Wound Care)
The global soft tissue allografts market is segmented and analyzed for demand and supply by application in orthopedics, dentistry, wound care, and others. Out of the four types of application, the dentistry segment is estimated to gain the largest market share over the projected time frame. The growth of the segment can be attributed to the rising number of tooth loss in the aging population, and tooth-related issues i.e., replacement of missing teeth in people that require effective treatment. For instance, until 2019, around 4 million people in the United States alone had dental implants, and this number is expanding by 520,000 annually.
Type (Cartilage, Tendon, Meniscus, Dental, Collagen, Amniotic Allograft)
The global soft tissue allografts market is also segmented and analyzed for demand and supply by type into cartilage allograft, tendon allograft, meniscus allograft, dental allograft, collagen allograft, and amniotic allograft. Amongst these six segments, the tendon allograft is expected to garner a significant share. The segment growth is attributed to rising cases of tendinitis and especially in older people. The most typical sites for tendinitis to develop with age include the Achilles tendon, hip, elbow, shoulder, and base of the thumb. This is due to the deterioration of bones and tissues as well as chronic diseases like diabetes and arthritis. According to the National Library of Medicine, adults over the age of 60 had a much greater incidence of rotator cuff tendon rupture, long head of the biceps tendon lesions, and rotator illnesses. Moreover, rising cases of tendon injuries during sports and other athletic activities are expected to augment segment growth. Around 30% of runners, 14% of volleyball players, and 12% of basketball players experience a tendon injury each year.
Our in-depth analysis of the global market includes the following segments:
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By Type |
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By Application |
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By End-User |
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North American Market Forecast
The North American soft tissue allografts market, amongst the market in all the other regions, is projected to hold the largest market share by the end of 2036. The growth of the market can be attributed majorly to the rising prevalence of arthritis, and rising healthcare expenditure on its treatment. In the United States, around 59 million adults, or approximately 24% of the population, suffer from arthritis. Osteoarthritis is the most prevalent type of arthritis. Gout and lupus are further kinds. Moreover, the annual cost of medical care for arthritis is around USD 300 billion. In addition to this, the surging need for rheumatoid arthritis treatment is another substantial factor that is estimated to boost the market growth further in the region over the projected time frame.
AlloSource, one of the leading providers of allograft in the United States, announced the launch of AlloMend Extra Large (XL) Acellular Dermal Matrix (ADM). It is so far the biggest dermal graft launched by the company. It is available in mesh and non-mesh variations for use in demanding soft tissue applications.
RTI Surgical, Inc. and Zimmer Biomet partnered with the American Academy of Implant Dentistry Foundation (AAIDF) to provide dental implants and wound care products for an initiative supporting veterans of the United States Armed Forces.
Author Credits: Radhika Pawar
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