Single Cell Genome Sequencing Market size was valued at USD 2.55 billion in 2023 and is likely to cross USD 17.96 billion by 2036, expanding at more than 16.2% CAGR during the forecast period i.e., between 2024-2036. In the year 2024, the industry size of single cell genome sequencing is estimated at USD 2.88 billion.
Single cell genome sequencing is a form of nucleic acid sequencing technology that analyzes the genomic sequence derived from a single cell to study its microenvironment as opposed to conventional sequencing technologies that use the mixture of genome isolated from a group of cells. The single cell genome sequencing market is expected to witness significant growth in the upcoming years owing to increasing prevalence of the genetic disorders, growing demand for targeted sequencing technologies, and recent advancement in DNA sequencing technology around the globe.
The recent advancement in the Next Generation Sequencing (NGS) technology has created a positive impact on the single genome sequencing market by accelerating the rapid development of the single cell sequencing methods including single cell whole-genome sequencing, single cell whole-exome sequencing, single cell whole-transcriptome sequencing and single cell epigenomic sequencing.
Over the past few years, the single cell genome sequencing has been utilized in various fields of biology, thus raising the demand for the single cell genome sequencing technology. Additionally, the single cell genome sequencing technology offers cell-specific genetic information that cannot be obtained with the help of traditional genome sequencing methods.
The increasing investment in various international research programs funded by the government as well as other organizations such as the World Health Organization is one of the major factors accelerating the market growth.
Furthermore, the healthcare spending has increased gradually over the years in various countries across the world, owing to the rising geriatric population and prevalence of chronic diseases, increase in the price of healthcare services, and others. Additionally, the increasing investment in the research and development sector is also expected to promote the market growth over the forecast period. For instance, according to the Health System Tracker, in U.S., the amount spent on health had more than doubled to USD 3.5 trillion in 2017 which include amount spent on healthcare and health-related activities comprising expenditures from both public and private funds. The advanced healthcare infrastructure of countries including the United States, Germany, UK, China, and others is also expected to aid the growth of the market.
Challenges
In low-income countries, due to the low healthcare expenditure and poor healthcare infrastructure, the availability of screening platforms is limited. Such factors combined with low spending on research and development activities in these countries is expected to act as barriers to the growth of the market.
There are extensive reimbursement challenges related to single cell genome sequencing procedures in the field of genetics. Several regulatory constraints associated with the development of the single cell genome sequencing technology are further expected to restrict the entry of new players, thus negatively impacting the market growth.
Base Year |
2023 |
Forecast Year |
2024–2036 |
CAGR |
16.2% |
Base Year Market Size (2023) |
USD 2.55 billion |
Forecast Year Market Size (2036) |
USD 17.96 billion |
Regional Scope |
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Based on the product segment, the single cell genome sequencing market is divided into reagents and instruments. Out of these, the instruments segment is presently capturing the largest market and is expected to grow with a CAGR of around 15% over the forecast period. This segment is further segmented into next generation sequencing systems, PCR instruments, microarrays and others, out of which, the next generation sequencing instruments segment is expected to occupy the largest market in the year 2020 by generating a revenue of around USD 450 million.
On the basis of application, the market is segmented into circulating tumor cells, cell differentiation/reprogramming, genomic variation, subpopulation characterization and others. The circulating tumor cells applications segment captured the largest market share 2.22% share in the year 2037 and is expected to grow at a CAGR of 16.37% over the forecast period.
The single cell genome sequencing market is segmented on the basis of end-user into hospitals, clinics, research & academic institutions and biotechnology & pharmaceutical companies. The research & academic institutions segment captured the highest market share in 2019 and is expected to reach a market share of around 4.45% in 2037. This is primarily attributed to the rise in investment by government and private entities to improve the research capacities for enhancing genomics studies across the globe as part of academic research.
Our in-depth analysis of the global market includes the following segments:
Product |
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Application |
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End-user |
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Single Cell Genome Sequencing Industry - Regional Synopsis
The single cell genome sequencing market in North America industry is set to account for largest revenue share of 42% by 2036. The growth in the region can be attributed to the increasing investments towards biotechnology, life-sciences, pharmaceutical, and medical device technologies from government and private entities to maintain the highest quality of services. The U.S. is the major country driving the growth of the market in the region on the back of rising adoption of innovative research practices in the country.
Europe is expected to attain second highest market size by 2028. It has been observed that with the availability of innovative technologies for genomics studies, there has been a rise in demand for effective products and solutions in the region for accurate sequencing of whole genome. Primarily driven by the demand from Germany, UK, France, & Italy, this region is expected to showcase high demand over the forecast period.
November, 2019: Thermo Fisher Scientific launched its first product in Next-Generation Sequencing platform- Ion Torrent Genexus System which would be able to deliver the specimen report on the same day.
April, 2020: Agilent Technologies Inc. and Mission Bio announced to join forces for developing Tapestri single-cell analysis platform.
May 2020: Roche launched a new KAPA series of exome and custom target enrichment portfolio which would offer sequencing facilities for translational and clinical research applications
Author Credits: Radhika Pawar
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