Psilocybin Assisted Therapy Market Analysis

  • Report ID: 4330
  • Published Date: Sep 30, 2025
  • Report Format: PDF, PPT

Psilocybin Assisted Therapy Market Segmentation:

Therapy Model Segment Analysis

Based on the therapy model, psilocybin with psychological support segment is projected to garner the largest revenue share of 75.6% in the psilocybin assisted therapy market during the forecast period. The dominance of the segment is attributable to its proven efficacy in clinical trials, allowing adoption by a wider group of the audience. Most of the prominent sources recognize that the therapeutic effect is not from the drug alone but from the combination with preparatory and integrative psychotherapy sessions, which are essential for processing the experience and achieving lasting clinical outcomes, hence denoting a positive market outlook.

End user Segment Analysis

In terms of the user specialty clinics segment, it is expected to attain a share of 60.4% in the psilocybin assisted therapy market by the end of 2035. The complex, resource-intensive nature of PAT, requiring controlled settings and specialized staff, makes this subtype the gold standard to generate revenue in this field. In June 2023, the U.S. FDA released its first-ever draft guidance for clinical trials involving psychedelic drugs such as psilocybin, LSD, and MDMA. Further, psychedelic compounds must meet the same scientific standards as other drugs, denoting the critical role of governing bodies in utilizing these elements.

Application Segment Analysis

Based on the application, the resistant depression segment is predicted to capture a share of 35.7% in the psilocybin assisted therapy market during the analyzed timeframe. The growth in the segment is highly subject to a critical unmet need with limited effective treatments, making it a primary target for clinical development. In November 2022, the Phase 2 trial, published in the NEJM, offers new evidence that a single 25 mg dose of psilocybin, combined with psychological support, can significantly reduce symptoms of treatment-resistant depression, which is a condition where patients have not responded to at least two prior antidepressants.

Our in-depth analysis of the psilocybin assisted therapy market includes the following segments:

Segment

Subsegments

Therapy Model

  • Psilocybin with Psychological Support
  • Psilocybin without Psychological Support

End user

  • Specialty Clinics
  • Hospitals
  • Research & Academic Institutes

Application

  • Treatment-Resistant Depression
  • Adults
  • Adolescents
  • Elderly
  • Major Depressive Disorder
  • End-of-Life Distress
  • Anxiety
  • Depression
  • Post-Traumatic Stress Disorder
  • Substance Use Disorders
  • Others
  • OCD
  • Anorexia

Source

  • Synthetic Psilocybin
  • Natural Psilocybin

Formulation

  • Liquid
  • Tablet
  • Capsule
  • Powder
  • Injection

Patient Demographics

  • Adults
  • Adolescents
  • Elderly
  • Veterans

Browse key industry insights with market data tables & charts from the report:

Frequently Asked Questions (FAQ)

In the year 2025, the industry size of the psilocybin assisted therapy market was over USD 3.1 billion.

The market size for the Psilocybin Assisted Therapy market is projected to reach USD 11.8 billion by the end of 2035, expanding at a CAGR of 15.8% during the forecast period, i.e., between 2026 and 2035.

The major players in the market are COMPASS Pathways plc, Cybin Inc., Mind Medicine (MindMed) Inc., ATAI Life Sciences N.V., Seelos Therapeutics, Inc., Numinus Wellness Inc., and others.

In terms of the therapy model, the psilocybin with psychological support is anticipated to garner the largest market share of 75.6% by 2035 and display lucrative growth opportunities during 2026-2035.

The market in North America is projected to hold the largest market share of 55.3% by the end of 2035 and provide more business opportunities in the future.
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