Pruritus Therapeutics Market Size & Share, by Disease Type (Atopic Dermatitis, Allergic Contact Dermatitis, Urticaria); Product - Global Supply & Demand Analysis, Growth Forecasts, Statistics Report 2025-2037

  • Report ID: 7174
  • Published Date: Feb 18, 2025
  • Report Format: PDF, PPT

Global Market Size, Forecast, and Trend Highlights Over 2025-2037

Pruritus Therapeutics Market size was over USD 9.3 billion in 2024 and is estimated to reach USD 15.4 billion by the end of 2037, expanding at a CAGR of 4.3% during the forecast timeline, i.e., 2025-2037. In 2025, the industry size of pruritus therapeutics is evaluated at USD 9.7 billion.

This skin disorder is mostly accompanied by several chronic conditions such as severe kidney, diabetes, and liver diseases, which fuels demand in the pruritus therapeutics market. As the cases of such comorbidities increase, the prevalence of associated eczema, psoriasis, xerosis, and dermatitis heightens. In addition, these dermatology-related issues are widely spread among a huge population of elderly and adolescent groups, driving the need for effective treatment. According to a journal, published in June 2023, the global prevalence of xerosis cutis was calculated to range between 29.0% and 85.0% in elder habitats. It further predicted that over 60.0% occurrence was registered for people with an average of 70 years old, which was reported to impact the quality of life significantly when originating from pruritus.

Thus, the rising incidences are pushing pharma leaders to cultivate tailored therapies to address specific needs for all categories, broadening the scope of innovation in the pruritus therapeutics market. The recent expansion and popularity attained by the targeted therapy segment have notably contributed to the sector’s growth. A Research Nester report predicted the 2037 and 2025 values of the precision medicine industry to attain USD 732.4 billion and USD 115.0 billion respectively, with a CAGR of 16.4%. Moreover, its positive impact has widened the exposure of dermatology through the inclusion of faster and cost-effective solutions. A 2022 NLM study on dermatologic disease-directed targeted therapy (D3T2) showcased a remarkable improvement in patient outcomes for psoriasis and atopic dermatitis.


Pruritus Therapeutics Market Size
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Pruritus Therapeutics Sector: Growth Drivers and Challenges

Growth Drivers

  • Evolving forms and methods of solutions: With advancements in precision dermatology, the expanding options in the pruritus therapeutics market are enhancing patient outcomes. Particularly, the ongoing innovations in biologics, corticosteroids, antihistamines, and other bio-based pharmacology products are helping produce more novel and accessible therapies. Additionally, the increased funding from both private and government organizations has accelerated R&D in this sector. For instance, in February 2024, a consortium led by Medicxi launched a new genre of pharmaceutical developing company, Alys Pharmaceuticals with an investment of USD 100.0 million to leverage R&D in immuno-dermatology.
  • Favorable regulatory and partnered operations: The contribution from the governments and regulations to improving healthcare access and spreading awareness about early detection & intervention has inflated the adoption of new remedies in the pruritus therapeutics market. In addition, the accelerated approvals from different regulatory bodies such as the FDA, PDMA, MHLW, Health Canada, and the European Union are empowering the globalization of available curatives. For instance, in September 2023, Cara Therapeutics earned USD 1.5 million as a milestone payment on gaining an MHLW allowance for its KORSUVA IV Injection Syringe, after receiving FDA approval in 2021.

Challenges

  • The economic burden of prescriptions: The high cost of dermatological remedies is the major cause behind the gap in accessibility in the pruritus therapeutics market. Most individuals, particularly from price-sensitive regions are unable to afford the prescribed medicines. This barrier may create an unavoidable hurdle in maximum adoption. In addition, the unawareness among dermatologists about budget consciousness while prescribing additional non-necessary therapies may discourage patients from investing in this sector, limiting the consumer base.
  • Variability in detection and treatment response: The absence of adequate tools or methods to identify the root cause of infection may impact the effectiveness of products from the pruritus therapeutics market. The uncertain predictability of this condition may result in incorrect or limited intervention, worsening the situation. In addition to this risk, the adverse reactions of these powerful medications may affect the quality of life, which further refrains adoption and delays regulatory approvals. It hinders the sector’s expansion.

Base Year

2024

Forecast Year

2025-2037

CAGR

4.3%

Base Year Market Size (2024)

USD 9.3 billion

Forecast Year Market Size (2037)

USD 15.4 billion

Regional Scope

  • North America (U.S., and Canada)
  • Asia Pacific (Japan, China, India, Indonesia, Malaysia, Australia, South Korea, Rest of Asia Pacific)
  • Europe (UK, Germany, France, Italy, Spain, Russia, NORDIC, Rest of Europe)
  • Latin America (Mexico, Argentina, Brazil, Rest of Latin America)
  • Middle East and Africa (Israel, GCC North Africa, South Africa, Rest of the Middle East and Africa)

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Pruritus Therapeutics Segmentation

Disease Type (Atopic Dermatitis, Allergic Contact Dermatitis, Urticaria)

In terms of disease type, the atopic dermatitis (AD) segment is poised to account for pruritus therapeutics market share of more than 31.5% by the end of 2037. Being one of the most common skin disorders and associated with several chronic conditions has made this sub-type a priority for health organizations across the world. An NLM article, released in December 2023, the estimated epidemiology of AD across the world accounted for a total of 204.0 million, among which, 101.27 million were adults and 102.78 million were children. They are penetrating offerings from this sector into the first-line itching management remedies through promotional programs and campaigns such as Atopic Dermatitis Research Network (ADRN). This is fueling the segment to captivate a major portion of revenue from this business.

Product (Corticosteroids, Antihistamines, Local Anesthetics, Counterirritants, Immunosuppressant, Calcineurin Inhibitors)

Based on product classification, the corticosteroids segment is anticipated to dominate the pruritus therapeutics market by the end of 2037. This class of compounds is pledged by its efficacy in a broad range of diseases. Its exceptional anti-inflammatory properties are widely utilized for reducing symptoms of associated itching and rashes, making it a globally desired component. According to OEC data, the value of the worldwide business of corticosteroids including cortisone, hydrocortisone, prednisone, and prednisolone reached USD 297.0 million in 2022, showcasing a rise of 17.0% from 2021. It also presented China to be the largest producer, registering an export value of USD 169.0 million in the same year.

Import-Export Database of Corticosteroids in Bulk:

Destination/Source

Import (in USD million)

Export (in USD million)

India

39.3

15.6

The U.S.

23.3

22.6

Italy

20.2

30.3

Source: 2022 OEC

Our in-depth analysis of the global pruritus therapeutics market includes the following segments:

Disease Type

  • Atopic Dermatitis
  • Allergic Contact Dermatitis
  • Urticaria
  • Others

Product

  • Corticosteroids
  • Antihistamines
  • Local Anesthetics
  • Counterirritants
  • Immunosuppressant
  • Calcineurin Inhibitors
  • Others

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Pruritus Therapeutics Industry - Regional Synopsis

North America Market Analysis

North America pruritus therapeutics market is projected to capture revenue share of around 40.3% by the end of 2037. The region is home to many global pharma producers including Cara Therapeutics, Bristol-Myers Squibb Company, Pfizer, Abbvie, and Eli Lilly and Company. In addition to that, the bigger consumer base and favorable standardization community of this marketplace are attractive to other leaders, ensuring a good flow of business. For instance, in July 2024, Arcutis Biotherapeutics gained allowance on supplemental new drug application (sNDA) for its ZORYVE (roflumilast) cream, 0.15%. It can be used as a rapid disease clearance and long-term solution for mild-to-moderate AD in adult and pediatric patients aged 6 and older.

The U.S. pruritus therapeutics market is fueled by enhanced healthcare spending and rigorous R&D activities in the pharmaceutical territory. These advancing efforts have escalated accessibility, convenience, and prompt services across the country, which significantly contributed to its expansion and attracted local drug developers to get involved. For instance, in January 2022, Pfizer received approval from the FDA to commercialize its solely developed Janus kinase 1 (JAK1) inhibitor, CIBINQO (abrocitinib). The designated once-a-daily dose of this oral therapeutic is curated to address refractory, moderate-to-severe atopic dermatitis in adult people, who did not benefit from other biologics or therapies.

Canada is augmenting the pruritus therapeutics market with the government efforts to control the widespread dermatology conditions such as related dermatitis. The authorities of the country are highly focused on cultivating a reliable network of medical facilities to ensure adequate services for every citizen, fostering a lucrative environment for domestic and foreign forces. In addition, sufficient financial support from subsidies and reimbursing policies are promoting more consumer engagement. For instance, in May 2021, the Ontario Exceptional Access Program and the New Brunswick Drug Plans Formulary enlisted DUPIXENT (dupilumab injection) from Sanfoi for patients of AD, aged 12 or older for public reimbursement.

APAC Market Statistics

The Asia Pacific pruritus therapeutics market is poised to witness the fastest CAGR in the world throughout the forecast period. The region is stepping forward with levitating advances in clinical trials to become a hub of pharmaceutical discoveries for every health category, including these skin irritations. On the other hand, the close association of dialysis with this disorder is increasing demand for related therapeutics with the rising cases of advanced nephropathy in developing countries such as China, Japan, Australia, and India. According to an NLM report, the number of individuals with advanced CKD was counted to be 65.6 million in 2023, where the risk factors included diabetes. This is conjugately attracting foreign forces to indulge their resources in this sector.

The growing bio-economy of India is the major driving factor in the pruritus therapeutics market. The ambitious goal of this country to leverage local production of drugs has created lucrative opportunities for global leaders. A PIB report estimated the domestic consumption of pharmaceutical products in India to account for USD 50.0 billion in FY 2023-24. It also mentioned the issuance of the Scheme for Promotion of Research & Innovation in Pharma Sector (PRIP) with an outlay of USD 571.4 million over 5 years. Further, the rising awareness and investments in medical infrastructure are propelling the need for these medicines to fulfill requirements for end-to-end services.

China is competing in the global landscape of the pruritus therapeutics market with its excellence in essential components such as corticosteroids. With a strong pharmaceutical manufacturing network, the country is forming a prominent presence in the international marketplace. Moreover, its predominant captivity over dialysis consumers is further consolidating its scope of leadership in the coming years. As of February 2021, over 2.5 million people in China were enrolled in different modalities of renal replacement therapy (RRT) including hemodialysis and peritoneal dialysis. The national annual spending on these treatments was calculated to be USD 50.0 billion, according to NLM. This testifies against the propagating growth of this landscape.

Pruritus Therapeutics Market Share
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Companies Dominating the Pruritus Therapeutics Landscape

    The worldwide pruritus therapeutics market is a highly competitive prefecture, where the key players are continuously evolving their offerings to consolidate their position. They are heavily investing in extensive R&D to introduce more effective and affordable pharmacology remedies to reduce the economic barrier. Their meticulous effort to upgrade product pipelines also brings diversity in available options, which is crucial for captivating a large base of consumers and globalization. For instance, in September 2024, Ipsen gained acceptance from the European Commision for marketing Kayfanda (odevixibat) for cholestatic pruritus in Alagille Syndrome (ALGS). This once-daily non-systemic ileal bile acid transport (IBAT) inhibitor brought a new choice for patients aged 6 months or older. Such key players are:

    • Abbvie, Inc.
      • Company Overview
      • Business Strategy
      • Key Product Offerings
      • Financial Performance
      • Key Performance Indicators
      • Risk Analysis
      • Recent Development
      • Regional Presence
      • SWOT Analysis
    • Actavis Plc
    • Amgen, Inc.
    • Bristol-Myers Squibb
    • Cara Therapeutics
    • GlaxoSmithKline, Plc. (GSK)
    • Myaln NV
    • Novartis AG
    • Pfizer Inc.
    • Sanofi
    • Teva Pharmaceuticals
    • Eli Lilly and Company

In the News

  • In November 2024, GSK revealed promising results from the global phase III clinical trial on its investigational targeted inhibitor, linerixibat for treating pruritus in primary biliary cholangitis. The results showcased the drug’s potential to cure the relentless itch associated with this rare autoimmune liver disease.
  • In September 2024, Eli Lilly and Company gained FDA approval for its targeted IL-13 inhibitor, EBGLYSS (lebrikizumab-lbkz) for the treatment of moderate-to-severe atopic dermatitis in adults and children aged 12 or over. This drug can deliver skin clearance within four weeks and itch relief as early as two weeks.

Author Credits:   Radhika Pawar


  • Report ID: 7174
  • Published Date: Feb 18, 2025
  • Report Format: PDF, PPT

Frequently Asked Questions (FAQ)

In the year 2024, the industry size of the pruritus therapeutics market was over USD 9.3 billion.

The market size for the pruritus therapeutics market is projected to reach USD 15.4 billion by the end of 2037 expanding at a CAGR of 4.3% during the forecast period i.e., between 2025-2037.

The major players in the market are Abbvie, Inc., Cara Therapeutics, GlaxoSmithKline, Plc. (GSK), Novartis AG, Pfizer Inc., Sanofi, Bristol-Myers Squibb, and others.

In terms of disease type, the atopic dermatitis segment is anticipated to garner the largest market share of 31.5% by 2037 and display lucrative growth opportunities during 2025-2037.

The market in North America is projected to hold the largest market share of 40.3% by the end of 2037 and provide more business opportunities in the future.
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