Protein Degeneration Therapy Market size was valued at USD 141 billion in 2024 and is likely to cross USD 674.9 billion by 2037, expanding at more than 12.8% CAGR during the forecast period i.e., between 2025-2037. In the year 2025, the industry size of protein degeneration therapy is estimated at USD 156.34 billion.
The reason behind the growth is due to the growing burden of cancer across the globe which is one of the leading causes of death driven by smoking, and other significant factors. For instance, in 2040, there will be more than 29 million cases of cancer worldwide owing to population growth and aging. Moreover, targeted protein degradation has increased the number of druggable proteins available for use in cancer treatments and is a strategy to destroy cancer-causing proteins.
The growing advancements in protein degeneration therapy are believed to fuel protein degeneration therapy market growth. For instance, the successful endogenous protein degradation tool known as proteolysis targeting chimeric (PROTAC) technology was created in recent years which has demonstrated promising outcomes in clinical trials for the treatment of breast and prostate cancer.
Growth Drivers
Challenges
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Base Year |
2024 |
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Forecast Year |
2025-2037 |
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CAGR |
12.8% |
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Base Year Market Size (2024) |
USD 141 billion |
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Forecast Year Market Size (2037) |
USD 674.9 billion |
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Regional Scope |
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Route of Administration (Oral, Intravenous)
The oral segment in the protein degeneration therapy market is estimated to gain a robust revenue share of 60% in the coming years. Owing to its ease of use, non-invasive drug delivery methods have drawn a lot of attention in the field of biomedicine. Oral protein degeneration therapies are developed so that patients can take them conveniently and easily.
Oral administration improves convenience and patient compliance and offers a simple, non-invasive method that lessens patient discomfort. Oral administration makes it possible for medications to be released more gradually since for many protein degeneration treatments, careful dosage is necessary. Moreover, this route of administration also encourages scalability and cost-effectiveness, may be easily scaled up for mass production, and may become more widely accepted by providing them to a broader range of patients.
Application (Inflammatory, Neurology, Oncological, Respiratory)
The neurology segment in the protein degeneration therapy market is set to garner a notable share shortly. The number of neurological disorders-related deaths and disabilities is becoming more widely acknowledged as a global public health concern since more than 6 million people worldwide lose their lives to neurological illnesses each year. The need for efficient therapies is growing as neurological disorders are becoming more common. Moreover, recognized genetic pathways or substantial protein deposits that cause cell death are used to describe neurodegenerative diseases. The goal of protein degeneration therapy is to remove the aberrant protein deposits while also slowing down the disease and trying to specifically remove these harmful proteins.
Our in-depth analysis of the global protein degeneration therapy market includes the following segments:
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Product Type |
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Route of Administration |
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Application |
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North American Market Forecast
North America industry is anticipated to hold largest revenue share of 35% by 2037. For instance, in 2021, U.S. health spending climbed by over 2% to reach around USD 4 trillion. Particularly, 2022 saw a faster-than-expected 4% increase in healthcare spending in the United States. As a result, the market for therapeutic proteins has experienced unprecedented growth, and new approaches to treating diseases have been made possible by protein-based therapies in the region.
European Market Statistics
The Europe protein degeneration therapy market is estimated to be the second largest, during the forecast timeframe led by growing awareness about quality health. The European Union's actions have resulted in a heightened consciousness regarding the significance of optimal health and overall well-being, leading to the growing desire for personalized approaches to address several health-related concerns.
Author Credits: Radhika Pawar
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