Parenteral Nutrition Market Trends

Growth Drivers

• An increase in cancer burden: The component of cachexia and malnutrition is increasingly available among cancer patients, which is positively driving the market’s demand. As per an article published by NLM in October 2022, malnutrition significantly affects 75% of overall cancer patients. In addition, an estimated 15% to 50% of cancer patients are affected with nutritional deficiencies, while 43% and 9% are impacted with overt malnutrition. This incidence readily increases during treatment procedures, reaching nearly 80% of patients, and can account for 20% of cancer deaths, depending on which there is a huge growth opportunity for the market.
• Advancements in pump and catheter design: The efficiency and safety of home parenteral nutrition are hugely dependent on vascular accessibility devices. The aspect of innovations in catheters and pumps has successfully made the global market manageable, leading to expanded adoption. According to the October 2022 NLM article, the utilization of in-line filters in pediatric-based parenteral nutrition constitutes a 1.2-micron in-line filter, suitable for lipid-containing admixture. Most importantly, a 0.22-micron filter is recommended to be readily utilized for non-lipid-containing admixtures, thus denoting an optimistic outlook for the overall market.
• Surge in the aging population: This is the single-most non-cyclical and robust driver for the market internationally. As stated in the October 2025 World Health Organization (WHO) article, the world’s population proportion is predicted to increase to 22% by the end of 2050, an increase from 12% as of 2015. Additionally, approximately 80% of older people will be residing across low- and middle-income nations by the end of the same year. Therefore, this increase in aging demographics denotes an upsurge in chronic conditions for which there is a huge demand for parenteral nutrition.

Long and Medium-Chain Formulation Differentiation Uplifting the Market (2024)

Source: NLM

Needles, Catheters, and Cannulae 2023 Export and Import Driving the Parenteral Nutrition Market

Source: OEC

Challenges

• Complexity in supply chain and logistics: The products in the market, particularly those comprising complex multi-vitamin cocktails and lipid emulsions, are frequently photosensitive and thermolabile. These need stringent protection from light and a cold-chain logistics system. Therefore, ensuring an end-to-end integrity from the manufacturing process to the patient's bedside is a massive challenge. This is extremely critical for home parenteral nutrition, wherein patients are required to administer storage and handling by themselves. Moreover, the worldwide supply chain fragility results in a severe shortage of necessary vitamins or amino acids, which jeopardizes patient care.
• Strict compliance and regulatory scrutiny:  As complex and biologic drug-nutrient combinations, parenteral nutrition-based formulations witness intensified administrative oversight from bodies such as the EMA and FDA. Any modification in composition, raw materials sourcing, and manufacturing process demands suitable regulatory clearance and extended validation. This eventually slows down the entry and innovation in the market. Therefore, this transition towards formulations denotes an increased compliance burden on manufacturers, needing to cater to good manufacturing practice (GMP).