Osteosarcoma Market Size & Share, by Type (Intramedullary Osteosarcoma, Juxtacortical Osteosarcoma, Extraskeletal Osteosarcoma); Diagnosis & Treatment; End user - Global Supply & Demand Analysis, Growth Forecasts, Statistics Report 2025-2037

  • Report ID: 6984
  • Published Date: Jan 14, 2025
  • Report Format: PDF, PPT

Global Market Size, Forecast, and Trend Highlights Over 2025-2037

Osteosarcoma Market size was estimated at over USD 800 million in 2024 and is poised to reach USD 1.7 billion by the end of 2037, expanding at a CAGR of 6.5% during the forecast timeline, i.e., 2025-2037. In 2025, the industry size of osteosarcoma is assessed at USD 852 million.

The increasing prevalence of cancer in the pediatric and adolescent populations is one of the drivers in the osteosarcoma market. Despite being a rare chronic condition, the targeted demography of this disease is a major health concern, affecting the well-being of future generations. According to NLM data, published in June 2022, 8,774,979.1 incident cases and 8,956,583.8 prevalent cases of cancer in children under 5 years were reported globally in 2019. The report further states, that around 80% of these childhood cancer cases can be successfully diagnosed and treated with proper healthcare arrangements. Thus, it is dragging the focus of the oncology industry on developing effective treatment and diagnostic solutions, driving growth in this sector.

Further, the high mortality and severity of such bone cancers in children is a strong propelling force behind the innovations in the osteosarcoma market. According to a study report, released in August 2021, the occurrence of malignant bone tumors (MBT) among children younger than 15 accounts 3-5%, which doubles by 7-8% for adolescents aged between 15-19. The study also showcased death events due to osteosarcoma being 37.5% within one year after diagnosis. The growing awareness about early detection pushes healthcare organizations to facilitate efficient devices and tools for better patient outcomes. In addition, the growing investment in R&D for advancements in oncology is creating a new pathway for this sector by introducing more effective bio-based and hybrid therapies.


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Osteosarcoma Sector: Growth Drivers and Challenges

Growth Drivers

  • Significant progress in oncology treatment: The introduction of advanced treatment methods such as precise medicine and targeted therapies is revolutionizing the osteosarcoma market. According to a Research Nester report, the precision oncology industry size is predicted to reach USD 387.5 billion by 2037 and is estimated to acquire USD 125.7 billion in 2025. Further, extension in the accessibility of innovative treatment is heavily contributing to the expansion and diversification of this sector. For instance, in May 2024, researchers at University College London introduced an efficient and cost-effective osteosarcoma treatment method, using gamma-delta T cells (gdT cells).
  • Favorable and strategic collaborations: Partnerships between several pharma companies, academic institutions, and public health organizations are fueling the osteosarcoma market. They are accelerating discoveries in this sector by playing a pivotal role in being a financial cushion and R&D guide, improvising disease management in bone cancer. For instance, in August 2023, the Bone Cancer Research Trust teamed with Hannah’s Willberry Wonder Pony Charity to allocate a grant of USD 0.2 million to facilitate R&D in this field. The funding was aimed at improving survival in patients with osteosarcoma (OS), fostering hope for global leaders to expand their network.

Challenges

  • High cost of treatment and new therapies: Expensive cancer treatment is a major setback in the osteosarcoma market. The prohibitive cost of advanced biologics and immunotherapies may cause financial drainage for patients and their families. This often limits the access to proper treatment for the survivors. In addition, the uncertainty of effectiveness may prevent them from investing in further procedures, particularly in low-income regions. 
  • Limited knowledge about its characteristics: Due to the rare events of this disease, people tend to lack awareness about the specific symptoms. This may hinder adoption in the osteosarcoma market, as early diagnosis or prevention is still unknown to them. Less understanding of the treatment process and associative outcomes can also discourage patients from enrolling. Additionally, the absence of deep knowledge about the disease mechanism makes it harder for companies to develop effective treatments.

Osteosarcoma Market: Key Insights

Base Year

2024

Forecast Year

2025-2037

CAGR

6.5%

Base Year Market Size (2024)

USD 800 million

Forecast Year Market Size (2037)

USD 1.7 billion

Regional Scope

  • North America (U.S., and Canada)
  • Asia Pacific (Japan, China, India, Indonesia, Malaysia, Australia, South Korea, Rest of Asia Pacific)
  • Europe (UK, Germany, France, Italy, Spain, Russia, NORDIC, Rest of Europe)
  • Latin America (Mexico, Argentina, Brazil, Rest of Latin America)
  • Middle East and Africa (Israel, GCC North Africa, South Africa, Rest of the Middle East and Africa)

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Osteosarcoma Segmentation

Type (Intramedullary Osteosarcoma, Juxtacortical Osteosarcoma, Extraskeletal Osteosarcoma)

Based on type, the intramedullary osteosarcoma segment is predicted to dominate osteosarcoma market share of over 84.1% by 2037. The segment is driven by the higher incidence rate of this type of MBTs. According to NLM data, published in December 2024, around 80% of the total osteosarcoma cases are reported to be high-grade intramedullary osteosarcoma. The malignancies mostly comprise long bones such as the femur, tibia, and humerus, among which 75-90% occur near the distal femoral, proximal tibial, or proximal humeral physis. Being such common in adolescents and younger adults (less than 25 years aged) puts it on prime focus of healthcare institutions to cultivate solutions.

End user (Hospitals & Clinics, Diagnostic Centers, Academic & Research Organizations)

In terms of end user, the hospitals and clinics segment is estimated to hold a significant share of the osteosarcoma market during the forecast period. The widespread of cancer hospitals and clinics across the world is fueling growth in this segment. The presence of qualified professionals and adequate infrastructure further increases investments in this sector by accommodating advanced diagnostic and treatment solutions. Besides government financing, the increased public expenditure on hospitals is also boosting demand in this segment. Moreover, the improved survival rates and surgical outcomes due to the availability of needed facilities have made hospitals a preferable option for patients to opt for treatment.

Our in-depth analysis of the global market includes the following segments:

Type

  • Intramedullary Osteosarcoma
  • Juxtacortical Osteosarcoma
  • Extraskeletal Osteosarcoma

End user

  • Hospitals & Clinics
  • Diagnostic Centers
  • Academic & Research Organizations

Diagnosis & Treatment

  • Treatment
    • Chemotherapy
    • Cisplatin
    • Doxorubicin
    • Epirubicin
    • Others
  • Surgery
    • Limb-Sparing Surgery
    • Amputation
    • Radiation Therapy
    • Others
  • Diagnosis
    • Imaging
  • Computerized Tomography (CT)
  • Magnetic Resonance Imaging (MRI)
  • X-Ray
  • Positron Emission Tomography (PET)
  • Others
    • Biopsies
  • Needle Biopsy
  • Surgical Biopsy
    • Blood Tests
  • Alkaline Phosphatase Profiling
  • Lactate Dehydrogenase Profiling
  • Others

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Osteosarcoma Industry - Regional Synopsis

North America Market Analysis

North America osteosarcoma market is predicted to hold revenue share of more than 47.6% by 2037. Continuous efforts to improve healthcare infrastructure are garnering a progressive environment for the oncology industry of this region. This is further propagating the regional progress in cancer care. Moreover, the wide network of cancer care centers across developing countries such as the U.S. and Canada is creating a more effective product line for this market. According to a report published by the National Cancer Institute (NCI) of the U.S., in December 2024, around 72 NCI-registered cancer care centers are situated in 36 states and the District of Columbia. The report further estimated that around 400,000 patients receive proper diagnosis from these institutions.

The U.S. is augmenting the regional growth in the osteosarcoma market with the advancement in oncology. The continuous discoveries from research institutions and academic organizations feedstock this sector with a diverse range of solutions. For instance, in August 2024, a clinical trial for immunotherapy afamitresgene autoleuecel led by Memorial Sloan Kettering Cancer Center received approval from the FDA. The newly introduced drug, Tecelra is capable of offering treatment for soft tissue cancers in adults.

Canada is proactively providing financial support to the domestic osteosarcoma market by investing in R&D to save children and adolescents from such life-threatening diseases. For instance, in January 2023, the national public health governing associations of this country allocated a grant of USD 23 million for building the Canadian Pediatric Cancer Consortium (CPCC). The joint initiative was aimed at leveraging domestic childhood cancer research, to help treat the increasing amount of child cancer patients.

APAC Market Statistics

Asia Pacific is poised to register a significant growth rate in the osteosarcoma market during the forecast timeline. Rising efforts from developing countries such as Japan, China, and India to elevate healthcare facilities, delivering better cancer care services. Collaborative government and private initiatives are further inspiring global leaders to participate in this landscape. Furthermore, accumulative healthcare expenditures in Western Pacific countries are presenting lucrative opportunities for this sector.

India is strengthening its foundation in the osteosarcoma market with its strong emphasis on the oncology industry. The governing bodies of this country are actively taking part in spreading awareness about such rare chronic diseases by promoting available treatment options. According to a PIB report, published in February 2023, the central government of India issued the Strengthening of Tertiary Cancer Care Centres Facilities Scheme to empower cancer care. A total of 19 State Cancer Institutes (SCIs) and 20 Tertiary Care Cancer Centres (TCCCs) were approved under this scheme.

China is establishing its leadership in the global osteosarcoma market by supplying high-quality oncology drugs. The manufacturing capabilities of this country is focusing on reducing economic burden by availing affordable treatment options in this sector. According to the NLM article, published in July 2022, 45 anticancer drugs were approved in China between the timeline, 2012-2021. HER2 was among the most commonly developed targets, which were further proven to have the potential to treat such bone cancers.

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Companies Dominating the Osteosarcoma Landscape

    Global leaders in the market are increasingly investing in drugs and therapy development for cancer treatment. They are now targeting rare types of chronic conditions including pediatric MBTs to expand their portfolio. This is expanding the marketplace by availing revolutionizing solutions in oncology. For instance, in March 2023, Pfizer announced an investment of USD 43 billion to acquire Seagen to globalize innovative cancer medicines. The company aimed at broadening its product pipeline toward transformative cancer therapeutics by cultivating bigger financial resources in this field. Such key players include:

    • Pfizer Inc.
      • Company Overview
      • Business Strategy
      • Key Product Offerings
      • Financial Performance
      • Key Performance Indicators
      • Risk Analysis
      • Recent Development
      • Regional Presence
      • SWOT Analysis
    • Bristol-Myers Squibb Company
    • Eli Lilly and Company
    • Teva Pharmaceutical Industries Ltd.
    • Baxter
    • Novartis AG
    • Aurobindo Pharma
    • Hikma Pharmaceuticals Plc.
    • Mylan N.V.
    • ADVAXIS, Inc.

In the News

  • In December 2024, Bristol Myers Squibb announced its progress in the exploration of potential in cell therapy for a range of cancers including blood cancer and bone marrow cancer. The company highlighted the expansion of its pipelines such as Breyanzi at the 66th American Society of Hematology (ASH) Annual Meeting and Exposition.
  • In February 2024, Novartis acquired MorphoSys AG at a per-share value of USD 70.08, aggregating USD 2.7 billion to globalize its oncology profile. This acquisition complements and empowers the company’s portfolio in cancer therapeutics through its expertise in innovations in biopharmaceuticals.

Author Credits:  Radhika Pawar


  • Report ID: 6984
  • Published Date: Jan 14, 2025
  • Report Format: PDF, PPT

Frequently Asked Questions (FAQ)

In the year 2024, the industry size of the osteosarcoma market was over USD 800 million.

The market size for the osteosarcoma market is projected to reach USD 1.7 billion by the end of 2037 expanding at a CAGR of 6.5% during the forecast period i.e., between 2025-2037.

The major players in the market are Pfizer Inc., Bristol-Myers Squibb Company, Eli Lilly and Company, Teva Pharmaceutical Industries Ltd., Baxter, Novartis AG, Aurobindo Pharma, Hikma Pharmaceuticals PLC, Mylan N.V., and ADVAXIS, INC., and others.

In terms of type, the intramedullary osteosarcoma segment is anticipated to garner the largest market share of 84.1% by 2037 and display lucrative growth opportunities during 2025-2037.

The market in North America is projected to hold the largest market share of 47.6% by the end of 2037 and provide more business opportunities in the future.
Osteosarcoma Market Report Scope
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