Orthobiologics Market Analysis

  • Report ID: 773
  • Published Date: Oct 07, 2025
  • Report Format: PDF, PPT

Orthobiologics Market Segmentation:

End User Segment Analysis

Hospitals, in the end-user sector of the orthobiologics market, are expected to capture the highest revenue market share of 41% in 2035. Hospitals are where most orthopedic procedures and intricate interventions take place that need high-end products of orthobiologics. This is due to their ability to purchase high volumes and provide adequate post-operative care, which enables them to achieve this share. According to data published by the American College of Rheumatology, more than 544,000 hip replacements and 790,000 knee replacements are done every year in the U.S. In addition, government funding and reimbursement schemes facilitate hospital adoption, stimulating segment growth.

Application Segment Analysis

The segment of orthopedic surgery is projected to hold a market share of 33% of the market by 2035. The growth of the market can be attributed to the rising incidence of osteoarthritis, trauma, and degenerative bone disorders, which demand surgical intervention. These types of conditions often need surgical interventions such as spinal fusion, joint reconstruction, fracture repair, and bone grafting, where orthobiologics like bone graft substitutes, platelet-rich plasma (PRP), bone morphogenetic proteins (BMPs), and stem cell-based therapies.  These therapies are extensively utilized to speed up healing, increase tissue regeneration, and enhance patient outcomes.

Source Segment Analysis

Autologous orthobiologics in the source segment are anticipated to achieve a 31% revenue in 2034 because of the reduced risk of immune rejection and improved healing percentages. Autologous products, which come from the tissue or cells of the patient, are utilized in the treatment plan in personalized therapy. Autologous therapies have also proven to be superior in bone regeneration, and based on this, the National Institute of Health Sciences Japan has encouraged their extensive use in all clinical therapies. Moreover, government policies for ensuring patient safety and quality standards again enhance the use of autologous sources, thus driving the growth of the sub-segment.

Our in-depth analysis of the market includes the following segments:

Segment

Subsegment

Product Type

  • Bone Graft Substitutes
  • Growth Factors
  • Stem Cell-Based Orthobiologics
  • Platelet-Rich Plasma (PRP)

Application

  • Orthopedic Surgery
  • Sports Medicine
  • Spine Surgery
  • Dental Procedures

Technology

  • Autologous
  • Allogeneic

End user

  • Hospitals
  • Ambulatory Surgical Centers
  • Specialty Clinics

Source

  • Autologous
  • Allogeneic

Browse key industry insights with market data tables & charts from the report:

Frequently Asked Questions (FAQ)

In the year 2026, the industry size of orthobiologics is evaluated at USD 7.70 billion.

The orthobiologics market size was valued at USD 7.46 billion in 2025 and is set to exceed USD 10.24 billion by 2035, registering over 3.23% CAGR during the forecast period i.e., between 2026-2035.

North America is anticipated to hold largest industry share of 39% by 2035.

The key market players include Stryker Corporation, Zimmer Biomet Holdings, Medtronic PLC, Smith & Nephew, NuVasive, Inc., Orthofix Medical Inc., Arthrex, Inc., Globus Medical, RTI Surgical, Wright Medical Group, BioMimetics Symbiosis, LifeNet Health and others.
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