Orthobiologics Market Size, by Solutions {Bone Graft Substitutes (Demoralized Bone Matrix, Bone Allografts, Bone Autographs, Bone Morphogenic Proteins, Bone Growth Stimulators), Visco-Supplementation (5, 3 Injection Visco-Supplementation, Single Injection Visco-Supplementation)}, Application (Spinal Fusion, Trauma Repair, Reconstructive Surgery), End-user (Clinics, Hospitals) - Growth Trends, Regional Share, Competitive Intelligence, Forecast Report 2025-2037

  • Report ID: 773
  • Published Date: Apr 18, 2025
  • Report Format: PDF, PPT

Orthobiologics Market - Historic Data (2019-2024), Global Trends 2025, Growth Forecasts 2037

Orthobiologics Market in 2025 is assessed at USD 8.85 billion. The global market size was valued at over USD 8.46 billion in 2024 and is projected to grow at a robust CAGR of 5.7%, surpassing USD 17.39 billion by 2037. North America is likely to hold the top spot, impelled by a rising geriatric population and increased healthcare expenditure.

The market growth primarily be ascribed to rising cases of bone diseases across the globe. Based on the report provided by the National Library of Medicine (NLM), it was observed that around 1.5 million people suffer from fractures owing to some sort of bone disease every year.

Growing prevalence of low immunity and calcium deficiency owing to changing lifestyles and skyrocketing spending on medical technology are projected to influence the market revenue. As of 2019, the total revenue generated by medical technology was anticipated to be nearly USD 450 billion while the R&D spending on this technology was estimated to be around USD 30 billion in the same year. Orthobiologics is an injectable therapy that utilizes biological substances to heal musculoskeletal injuries rapidly. The substances used in the therapy are made from the materials naturally produced by the body.


Orthobiologics-Market Size
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Orthobiologics Sector: Growth Drivers and Challenges

Growth Drivers

  • Growing Number of Bone Fractures to Boost the Market Growth
  • For instance, the estimated number of bone fractures received is approximately 1000 fractures per 100,000 people every year.
  • Increasing Sales of Orthopedic Devices
  • As of 2022, the orthopedic devices segment was valued at around USD 40 billion.
  • A wide array of technologies is included in orthobiologics to improve the functionality of the broken bone. Components such as, scaffolds to reinforce tissue, cell therapies, and bone grafting materials are used in the therapy. Orthobiologics is associated with bone injuries, for instance, osteoporosis, osteonecrosis, bone infection, and density.
  • Higher Prevalence of Orthopedic Injuries
  • The prevalence of orthopedic injuries can be observed by the fact that more than 6 million orthopedic surgeries are performed every year solely in the USA.
  • Rising Cases of Osteoporosis Across the Globe
  • It is observed that 1 in 2 women and 1 in 5 men aged 50 or over suffer from osteoporosis globally. Furthermore, in 2017-18, more than 18% of women were predicted to be living with osteoporosis.
  • Significant growth in the Healthcare Expenditure
  • World Bank published statistics showing that in 2019, the healthcare expenditure reached 1,121.9 U.S. dollars per Capita.

Challenges

  • Higher Cost Associated with the Treatment
  • Lack of Skilled Medical Professionals and Requisite Technology
  • Presence of the Alternatives in the Market

Base Year

2024

Forecast Year

2025-2037

CAGR

5.7%

Base Year Market Size (2024)

USD 8.46 billion

Forecast Year Market Size (2037)

USD 17.39 billion

Regional Scope

  • North America (U.S. and Canada)
  • Asia Pacific (Japan, China, India, Indonesia, South Korea, Malaysia, Australia, Rest of Asia Pacific)
  • Europe (UK, Germany, France, Italy, Spain, Russia, NORDIC, Rest of Europe)
  • Latin America (Mexico, Argentina, Brazil, Rest of Latin America)
  • Middle East and Africa (Israel, GCC North Africa, South Africa, Rest of the Middle East and Africa)

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Orthobiologics Segmentation

End-user (Clinics, Hospitals)

The hospitals segment in the orthobiologics market is projected to witness noteworthy growth over the forecast period. The growth of the segment can be accounted to the rising patient pool in hospitals worldwide. For instance, in 2019, approximately 7% of the US population was noticed to be hospitalized.

Our in-depth analysis of the global orthobiologics market includes the following segmen

          By Solutions

  • Bone Graft Substitutes
  • Demoralized Bone Matrix
  • Bone Allografts
  • Bone Autographs
  • Bone Morphogenic Proteins
  • Bone Growth Stimulators
  • Visco-Supplementation
  • 5 and 3 Injection Visco-Supplementation
  • Single Injection Visco-Supplementation

           By Application

  • Spinal Fusion
  • Trauma Repair
  • Reconstructive Surgery

          By End-User

  • Clinics
  • Hospitals

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Orthobiologics Industry - Regional Synopsis

The North America region is expected to hold majority market share by the end of 2037. The growth of the market can be ascribed to rising geriatric population with severe bone diseases and the ongoing development in the healthcare expenditure of the region. As per the data published by the World Bank, it was noticed that the geriatric population in the United States reached 56,545,938 in 2021.

Orthobiologics-Market-Share
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Companies Dominating the Orthobiologics Landscape

    • Medtronic plc
      • Company Overview
      • Business Strategy
      • Key Product Offerings
      • Financial Performance
      • Key Performance Indicators
      • Risk Analysis
      • Recent Development
      • Regional Presence
      • SWOT Analysis
    • Wright Medical Group N.V. 
    • Zimmer Biomet Holdings, Inc.
    • Arthrex, Inc.
    • Medical Device Business Services, Inc.
    • Johnson & Johnson & Services, Inc.
    • RTI Surgical, Inc.
    • MTG Learning Media Pvt. Ltd.
    • Bioventus LLC
    • Stryker Corporation

In the News

  • Johnson & Johnson & Services, Inc.’s Janssen Pharmaceutical Company to announce its acquisition of U.S. FDA approval for IMBRUVIGA (ibrutinib). IMBRUVIGA is a BTKi treatment for pediatric patients with chronic graft-versus-host disease (cGVHD) after the failure of systemic therapy.
  • Zimmer Biomet Holdings, Inc. announces its three-year agreement with Hospital for special surgery (HSS). The agreement is established to make HSS/Zimmer Biomet (ZB) Innovation Center for Artificial Intelligence (AI).

Author Credits:   Radhika Pawar


  • Report ID: 773
  • Published Date: Apr 18, 2025
  • Report Format: PDF, PPT

Frequently Asked Questions (FAQ)

2025 Orthobiologics Market is assessed at USD 8.85 billion.

The global orthobiologics market size was valued at over USD 8.46 billion in 2024 and is projected to grow at a robust CAGR of 5.7%, surpassing USD 17.39 billion by 2037.

North America is likely to hold the top spot, impelled by a rising geriatric population and increased healthcare expenditure.

The major players in the market include Wright Medical Group N.V., Zimmer Biomet Holdings, Inc., Arthrex, Inc., Medical Device Business Services, Inc., Johnson & Johnson & Services, Inc., RTI Surgical, Inc., MTG Learning Media Pvt. Ltd., and others.
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