Nucleic Acid Isolation and Purification Market Trends

Growth Drivers

• Increasing burden of chronic diseases: One of the major contributors to the nucleic acid isolation and purification market is the rising burden of chronic diseases such as cancer, genetic disorders, and infectious diseases. This, in turn, necessitates the requirement for nucleic acid testing. In this regard CDC report in 2024 reported more than 2.1 million cases of cancer require biomarker testing that fuels the demand for isolation kits. Besides, as there is a 12% increase in rare genetic disorders in Europe, the reliance on PCR and NGS-based purification increases further, reflecting a positive market adoption.

• Personalized medicine expansion: There is a heightened usage of gene therapies and personalized medicine in the vast healthcare sector. In this regard, the U.S. FDA in 2024 states that its approval for more than 10 gene therapies requires ultra-pure DNA or RNA isolation. Besides, the NHS in 2023 notifies that a clinical study in the U.K. found that these personalized cancer treatments remarkably increased the demand for extraction kit by more than 35% thus readily augmenting market expansion.

Manufacturer Strategies Shaping Nucleic Acid Isolation and Purification Market Expansion

There is a huge opportunity for manufacturers involved in the market who are putting constant efforts to strengthen their global ecosystem. Key trends figured by the players include automation, collaborations, and a substantial increase in domestic production. For instance, in 2023, Thermo Fisher Scientific announced the launch of KingFisher Revv, which increased its revenue by USD 225 million. Besides WHO report in 2024 states that the future growth in the market extensively relies on affordable solutions in the developing nations, where more than 50% of labs are still leveraging manual methods.

Revenue Opportunities for Manufacturers (2023–2024)

Feasible Expansion Models Shaping the Nucleic Acid Isolation and Purification Market

The global nucleic acid isolation and purification market is witnessing expansion shaped by various feasibility models such as partnerships with domestic firms, strategic pricing, and offering automation as a service. In this regard, it is reported that Tata Medical partnered with Illumina, intending to offer affordable extraction systems that increased revenue by 14% from 2022 to 2024.  Furthermore, the CDC invested USD 55 million in decentralized testing hubs that substantially expanded access to automated extraction in the rural clinics of the U.S. Hence, these models are anticipated to readily blister the market progression during the forecast timeline.

Feasibility Models for Market Expansion

Challenge

• Cost limitations in developing nations: This is one of the major restraints in the nucleic acid isolation and purification market that hinders adoption in price-sensitive regions. WHO states that above 78% of labs in Africa witness funding shortages, due to which they can’t afford 5 test kits. To mitigate this, Bio-Rad offered a kit for USD 1.5 that gained a 16% increased share in Kenya. Besides, the funding subsidies are offering only 28%, which diminishes the industry adoption among people belonging to low-income nations.