Multiple System Atrophy Market Analysis

  • Report ID: 3440
  • Published Date: Oct 03, 2025
  • Report Format: PDF, PPT

Multiple System Atrophy Market Segmentation:

Treatment Segment Analysis

The pharmacological segment in the multiple system atrophy market is expected to account for the largest share of 92.5% by the end of 2035. The segment’s growth is highly attributed to the complete absence of cleared disease modifying therapy options for the disease. Besides, the present standard of care depends on off-label drugs to effectively manage the disorder’s critical and advanced symptoms. This readily includes midodrine for orthostatic hypotension, levodopa for parkinsonism, and different medications for issues, such as rigidity, sleep disorders, and urinary incontinence. Meanwhile, the increased expenses of these rare regimens, along with unmet requirements has solidified the segment’s intervention in the overall MSA market.

Drug Class Segment Analysis     

Disease-modifying therapies segment in the market is predicted to cater to the second-largest share during the projected period. The segment’s development is highly fueled by successfully addressing the underlying disease process, which readily halted its overall progression, in comparison to managing symptoms. According to an article published by NLM in September 2025, the multiple sclerosis incidence has surged by 15.4%, denoting an increase from 210.5 to 243.1 per 100,000 population, thus suitable for the segment’s upliftment and effectively administering diseases.

Type Segment Analysis

The MSA-cerebellar (MSA-C) segment in the multiple system atrophy market is anticipated to constitute the third-largest share by the end of the forecast duration. The segment’s upliftment is highly driven by its atrophy, owing to the disease leading to significant motor control loss resulting in critical problems with movement, coordination, and balance. As per the January 2023 NLM article, the MSA pre-dominance among men and female accounts for 1.3:1 ratio, owing to its rareness and yearly incidence of 0.1 to 3.0 per 100,000, depending on geographic location and age criteria. Besides, abnormalities among traditional 1.5 MRI in patients with the disease tend to include lower brainstem atrophy, cerebellum, middle cerebellar peduncles.

Our in-depth analysis of the multiple system atrophy market includes the following segments:

Segments

Subsegments

Treatment

  • Pharmacological
  • Non-Pharmacological
    • Therapy
    • Supportive Care

Drug Class

  • Disease-Modifying Therapies (Novel Pipeline)
    • Pharmacological
    • Non-Pharmacological
  • Symptomatic Treatments

Type

  • MSA-Cerebellar (MSA-C)
  • MSA-Parkinsonian (MSA-P)

Route of Administration

  • Intravenous
  • Oral
  • Subcutaneous

Distribution Channel

  • Specialty Pharmacies
  • Hospital Pharmacies
  • Retail Pharmacies

Diagnosis

  • Magnetic Resonance Imaging (MRI)
    • Specialty Pharmacies
    • Hospital Pharmacies
    • Retail Pharmacies
  • Positron Emission Tomography (PET)
  • Single Photon Emission Computed Tomography (SPECT)
  • Tilt Table Test
  • Others

Browse key industry insights with market data tables & charts from the report:

Frequently Asked Questions (FAQ)

In the year 2025, the industry size of the multiple system atrophy (MSA) market was over USD 150.1 million.

The market size for the multiple system atrophy (MSA) market is projected to reach USD 230.8 million by the end of 2035 expanding at a CAGR of 4.9% during the forecast period i.e., between 2026-2035.

The major players in the market are Biogen, Roche, UCB, Lundbeck, and others.

In terms of the treatment segment, the pharmacological segment is anticipated to garner the largest market share of 92.5% by 2035 and display lucrative growth opportunities during 2026-2035.

The market in North America is projected to hold the largest market share of 44.7% by the end of 2035 and provide more business opportunities in the future.
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