Global Methotrexate Drug Market TOC
Methotrexate Drugs Market size was valued at USD 584.09 million in 2024 and is set to exceed USD 846.99 million by 2037, registering over 2.9% CAGR during the forecast period i.e., between 2025-2037. In the year 2025, the industry size of methotrexate drugs is estimated at USD 597.64 million.
The demand for methotrexate drugs is owing to the increasing use of the drugs for various inflammatory diseases such as rheumatoid arthritis, juvenile rheumatoid arthritis, and lupus. About 60% of people with rheumatoid arthritis are presently taking methotrexate, which is the recommended first-line treatment for rheumatoid arthritis, according to the American College of Rheumatology.
Moreover, the rising prevalence of autoimmune diseases is driving the demand for methotrexate drugs across the globe. As manufacturers are focusing on innovating new drugs in order to reduce the challenges faced by patients.
Growth Drivers
Challenges
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Base Year |
2024 |
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Forecast Year |
2025-2037 |
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CAGR |
2.9% |
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Base Year Market Size (2024) |
USD 584.09 million |
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Forecast Year Market Size (2037) |
USD 846.99 million |
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Regional Scope |
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Disease Type (Cancer, Autoimmune Diseases, Ectopic Pregnancy)
The cancer segment in the methotrexate drugs market is expected to grow at a CAGR of 3.2% during the forecast period. Methotrexate drugs slows down the growth of cancer cells. The growth of the segment is due to the rising incidence rates of various types of cancers across the globe. For instance, according to the National Cancer Institute, Prostate, lung, and colorectal cancers account for an estimated 43% of all cancers diagnosed in men in 2020. For women, the three most common cancers are colorectal, breast, and lung which accounted for an estimated 50% of all new cancer diagnoses in women in 2020. In addition, higher usage of methotrexate in cancer treatment than in arthritis or psoriasis is also a major factor catering to the segment’s growth in the market. It is the initial treatment administered to cancer patients and is also used in combination therapy. In Japan, methotrexate is administered as the first-line treatment for cancer.
End-User (Hospitals, Specialty Clinics, Home Healthcare)
Methotrexate drugs market from the hospital segment is expected to garner a significant share by 2037, due to the increasing influx of patients with target diseases. Methotrexate is a kind of chemotherapy, and it is a treatment for a variety of cancers. According to the National Library of Medicine, in the United States, an estimated 60,000 cancer patients with cancer are hospitalized each year for chemotherapy. As the number of patients seeking treatment at hospitals continues to rise, the segment is further expected to grow with the highest CAGR of 3.3% during the forecast period. Besides, specialty clinics are expected to grow at a significant growth rate.
Our in-depth analysis of the global methotrexate drugs market includes the following segments:
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Dosage Form |
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Drug Type |
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Disease Type |
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Route of Administration |
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End-User |
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North American Market Forecast
The North America methotrexate drugs market is projected to hold a significant market share of 41% by the end of 2037. The demand for methotrexate drugs is propelling in the region due to its high adoption of innovative technologies, and higher healthcare expenditures. In addition, the immediate availability of methotrexate pharmacotherapy, growing research and development linked to methotrexate drugs, multiple cancer survivor campaigns, high rates of psoriasis and arthritis, and the accessibility of reimbursement policies are also expected to contribute to regional growth. Also, the rising number of products and drugs that have been approved by the authorities. For example, U.S. specialty pharmaceutical company Cumberland Pharmaceuticals Inc. announced the launch of her RediTrex injection in November 2020. RediTrex is a new prefilled syringe specifically designed for ease of Use and precise dosing for subcutaneous administration of methotrexate in patients with rheumatoid arthritis and psoriasis.
APAC Market Statistics
The Asia-Pacific methotrexate drugs market is predicted to have notable growth during the forecasted timeframe. The demand for methotrexate drugs in the region is majorly due to the increasing awareness of different medical modalities. Moreover, there are surging number of female populations requiring a medical abortion in the Asia Pacific region.
Author Credits: Radhika Pawar
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