Leucovorin Calcium Market size was over USD 26.98 million in 2024 and is poised to exceed USD 187.87 million by 2037, witnessing over 16.1% CAGR during the forecast period i.e., between 2025-2037. In the year 2025, the industry size of leucovorin calcium is estimated at USD 34.38 million.
The growth of this market can be attributed to the growing presence of cancer patients globally. Leucovorin calcium is widely used to treat cancer patients in the chemotherapy process it is used as an effective drug in the treatment. In 2020, around 20 million cancer cases were recorded all over the world.
Rising blood cells disorder such as anemia, thrombocytopenia, and neutropenia that is caused by high doses of an antagonist such as methotrexate, trimethoprim, and pyrimethamine are significant factor anticipated to drive the industry growth. In addition, growing cases of megaloblastic anemia caused by folic acid deficiency are expected to drive the market growth of the leucovorin calcium market in the forecast period. Leucovorin calcium is used to treat megaloblastic anemia in cases when oral therapy is not feasible. About 1 in 7.5 thousand people develop megaloblastic anemia in the United States every year.
Growth Drivers
Challenges
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Base Year |
2024 |
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Forecast Year |
2025-2037 |
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CAGR |
16.1% |
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Base Year Market Size (2024) |
USD 26.98 million |
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Forecast Year Market Size (2037) |
USD 187.87 million |
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Regional Synopsis |
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End-user (Hospital, Retail Pharmacies, Specialty Clinics)
The global leucovorin calcium market is segmented and analyzed for demand and supply by end users into hospitals, retail pharmacies, specialty clinics, and others. Out of these, the hospital segment is anticipated to hold the largest market share by the end of 2037. The expansion of the healthcare system and the fact that the drug is not widely accessible and must be purchased with a prescription from a doctor both contribute to the market's growth. Also, the presence of growing cases of cancer and critical blood cell disorder raises the demand for the hospital segment globally. For instance, 1.25 million new instances of blood cancer, or about 6% of all cancer cases, are recorded annually. Leucovorin calcium is typically used for the treatments such as Hodgkin's lymphoma, ovarian cancer, colorectal cancer, and brain tumors. Leucovorin calcium has been used more frequently in hospital pharmacies as a result of its expanding potential for treating various malignancies, particularly colon cancer.
Route of Administration (Oral, Injectable)
The global leucovorin calcium market is segmented and analyzed for demand and supply by route of administration into oral, injectable, and others. Out of these, the injectable segment is anticipated to hold the largest market share by the end of 2037. Leucovorin is a medicine that consists of an active ingredient named leucovorin. It appears in injection form for application by intravenous infusion, intramuscularly into the under the skin of the stomach, muscle, or arm. The injection is found at API with sodium chloride, water for injection, and sodium hydroxide, or hydrochloric acid as a buffer.
Our in-depth analysis of the global market includes the following segments:
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By Route of Administration |
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By End User |
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North American Market Forecast
North America industry is set to hold largest revenue share by 2037. This can be attributed owing to the presence of major pharmaceutical companies in the region backed by the high healthcare expenditure in the developed countries. As per the data by the U.S. Centers for Medicare & Medicaid Services, the national healthcare expenditure grew by 9.7% to USD 4.1 trillion in 2020. Owing to the presence of significant important companies and advanced healthcare infrastructure in the area, North America is anticipated to hold the biggest market share. Also, a rising number of people with blood disorders and colorectal cancer patients are boosting the region's leucovorin calcium market.
Europe Market Forecast
The market in the Europe region is estimated to witness noteworthy growth by the end of 2037. This can be attributed to the growing prevalence of cancer, along with the efficient healthcare system in the region. Europe is one of those countries in the world that has favorable health care policies and also has enhanced health care practices for the treatment of cancer. Countries such as Germany, and the UK have favorable reimbursement policies and established regulatory frameworks, they focus on patient safety, constantly monitor patients' health while the treatment is going on, and also treatment efficiency standards are high level these are a few significant factors that are estimated to drive the market growth.
APAC Market Statistics
The market in the Asia Pacific region is also anticipated to hold a significant market share by the end of 2037. Geriatric population growth; infrastructural improvements in the healthcare sector; and an increase in R&D activity in Asia-Pacific developing countries. Increasing product recalls since leucovorin calcium-drug interactions and supply problems as a result of restrictions on the import of raw materials into the United States, China, and India are a few of the challenges facing the worldwide leucovorin calcium market. Throughout the forecast period, an increase in launch prices is anticipated to present growth prospects for businesses active in this market. Moreover, the market is also expected to grow with the improving healthcare infrastructure in the region and growing awareness about cancer disease, its causes, and its treatment options in the region.
Author Credits: Radhika Pawar
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