Gastroesophageal Reflux Disease Market Trends

  • Report ID: 5075
  • Published Date: May 05, 2025
  • Report Format: PDF, PPT

Gastroesophageal Reflux Disease (GERD) Sector: Growth Drivers and Challenges

Growth Drivers

  • Introduction of innovative treatment approach: The rising popularity of preventive measures is gaining traction in the gastroesophageal reflux disease (GERD) market. As people gain knowledge and awareness about the importance of early detection and intervention to stop the condition from worsening grows, adoption and development in the diagnosis category increases. For instance, in April 2023, Laborie Medical Technologies introduced a wireless pH-capsule reflux testing system, alpHaONE, to identify GERD and generate monitoring data up to 96 hours. Similarly, the introduction of minimally invasive and endoscopic procedures is creating new long-term options for patients, diversifying the pipeline.

  • Global expansion of over-the-counter (OTC) medicines: Besides the improvement in direct-to-customer services, the easy availability of generic solutions is also boosting revenue generation in the market. According to a 2020 NLM article, up to 1,00,000 marketed products in the U.S. belonged to the OTC medications, which saved a total of USD 102.0 billion in the national healthcare expenditure. Medicines from this category, such as antacids and low-dose PPIs, are enhancing public access to disease management, fueling growth in this sector. Moreover, MedTech companies are also creating diagnostic OTC products to mitigate the accessibility issues in this sector from every aspect.

Challenges

  • Limitations in long-term efficacy and accurate prognosis: Despite the growth in availability and accessibility in the market, there are major adverse effects of this scenario. One of them is the misuse of OTC drugs among older citizens. In addition, the use of mainstay treatment such as PPIs for a long-run may cause severe side-effects, such as kidney disease, bone fractures, and gut microbiome disruption. Thus, the growing safety concerns about these products are slowing the global expansion in this field. To mitigate this roadblock, companies must invest more in extensive R&D to develop safer alternatives such as disease modifying therapeutics. 


Base Year

2024

Forecast Year

2025-2037

CAGR

2.4%

Base Year Market Size (2024)

USD 5.24 billion

Forecast Year Market Size (2037)

USD 7.13 billion

Regional Scope

  • North America (U.S., and Canada)
  • Asia Pacific (Japan, China, India, Indonesia, Malaysia, Australia, South Korea, Rest of Asia Pacific)
  • Europe (UK, Germany, France, Italy, Spain, Russia, NORDIC, Rest of Europe)
  • Latin America (Mexico, Argentina, Brazil, Rest of Latin America)
  • Middle East and Africa (Israel, GCC North Africa, South Africa, Rest of the Middle East and Africa)

Browse key industry insights with market data tables & charts from the report:

Frequently Asked Questions (FAQ)

In the year 2025, the industry size of gastroesophageal reflux disease is evaluated at USD 5.44 billion.

The gastroesophageal reflux disease market size was valued at USD 5.24 billion in 2024 and is set to exceed USD 7.13 billion by 2037, expanding at over 2.4% CAGR during the forecast period i.e., between 2025-2037. Higher consumption of processed food, increase in digestive issues, and problems caused by contaminated food will boost the market growth.

North America industry is predicted to dominate majority revenue share of 35% by 2037, owing to rising aging population in the region which are more prone to gastrointestinal problems.

The major players in the market are AstraZeneca PLC, Eisai Co., Ltd., GSK plc., Takeda Pharmaceutical Company Limited., Ironwood Pharmaceuticals, Inc., Johnson & Johnson Services, Inc., SFJ Pharmaceuticals, Sebela Pharmaceuticals, Phathom Pharmaceuticals, Inc., Camber Pharmaceuticals, Inc.
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