Estrogen Replacement Therapy Market Analysis

  • Report ID: 2374
  • Published Date: Jun 03, 2025
  • Report Format: PDF, PPT

Estrogen Replacement Therapy Segmentation

Route of Administration (Oral Therapy, Transdermal Therapy, Injectable Therapy, Topical Therapy)

Based on the route of administration, the oral therapy segment is expected to dominate the estrogen replacement therapy market with a share of 45.2% by the end of 2037. Cost-effectiveness and patient convenience are the major factors behind the segment's leadership over other methods. This can also be displayed through the predominant captivity of oral prescriptions as per the preference of service providers and physicians. In this regard, in 2024, the Centers for Medicare & Medicaid Services revealed that 70.3% of the total ERT prescribed across the U.S. consisted of oral formulations. Furthermore, the widespread utilization of these solutions reflects its easy accessibility, solidifying the segment's dominance.

Application (Menopause Treatment, Osteoporosis Management, Hypogonadism Treatment)

In terms of applications, the menopause treatment segment is poised to hold the largest share of 50.4% in the estrogen replacement therapy market throughout the discussed timeframe. As the enlarging population of post-menopausal women around the globe becomes aware of hormonal imbalance-associated health issues, ERT is becoming a priority for dedicated clinical authorities. In addition, the emergence of medical studies and trials, demonstrating its high efficacy is amplifying investments from this discipline. Based on such validation, more hospitals and outpatient care settings are incorporating these therapies as a part of their modernization strategy. These demographic trends and international recognition are positioning this segment as the cornerstone application in this sector.

Our in-depth analysis of the global estrogen replacement therapy market includes the following segments: 

Route of Administration

  • Oral Therapy
  • Transdermal Therapy
  • Injectable Therapy
  • Topical Therapy

Application

  • Menopause Treatment
  • Osteoporosis Management
  • Hypogonadism Treatment

Distribution Channel

  • Hospital Pharmacies
  • Retail Pharmacies
  • Online Pharmacies 

Browse key industry insights with market data tables & charts from the report:

Frequently Asked Questions (FAQ)

Currently in 2025, the industry revenue of estrogen replacement therapy market is evaluated at USD 13.7 billion.

The global estrogen replacement therapy market is set to rise from USD 12.8 billion in 2024 to USD 26.1 billion by 2037, witnessing a CAGR of more than 6.6 % throughout the forecast period, between 2025 and 2037.

North America industry is poised to dominate majority revenue share by 2037, driven by rising number of older women undergoing the menopause, which is increasing the demand for estrogen therapy in order to provide comfort and make daily life easier.

The major players in the market are Abbott Laboratories, Pfizer Inc., Novartis, Bayer Healthcare, Eli Lilly, Novo Nordisk, Merck, Allergan, Orion Pharma and TherapeuticsMD, Inc.
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