Esketamine Nasal Spray Market Share

  • Report ID: 5318
  • Published Date: Nov 25, 2025
  • Report Format: PDF, PPT

Esketamine Nasal Spray Market - Regional Analysis

North American Market Insights

North America industry is estimated to hold largest revenue share of 38% by 2035. The major factor that is expected to boost the esketamine nasal spray market growth in the region is the increasing prevalence of depressed Americans. A calculated 2 million times each year, people with severe mental health situations are jailed or imprisoned in the U.S. Women are inordinately influenced at twice the rate as men. For this population, detention may worsen pre-existing indications. In fact, while the percentage of U.S. adults getting mental health therapy rose from 19.2% in 2019 to 21.6% in 2021, 42% of U.S. adults with an identifiable situation reported in 2023 that they could not afford to avail the therapy they required. A trio of new studies paints a gloomy picture of how overdose deaths, depression, and obstacles to care are burdening heaviest on unprivileged and minority people - and are arranging to broaden health discrepancies as the U.S. appears from the pandemic.

European Market Insights

The esketamine nasal spray market in the Europe region is poised to show a notable growth in the upcoming years. The consumption of antidepressant drugs (AD) and esketamine nasal spray has grown drastically in the last two decades in the Europe region The implementation of antidepressants grew by almost two and a half times from 2000 to 2020 in 18 European countries, in line with the Organization for Economic Cooperation and Development (OECD) data. The average antidepressant ingestion around 18 European countries was 30.5 DDD per 1,000 people per day in 2000 increasing to 75.3 DDD in 2020, a 147 per cent rise.  The European Parliament has always been an advocate of the encouragement of good mental health and keeping mental health at the heart of EU managerial. Its Subcommittee on Public Health (SANT) is recently developing its initiative report on mental health.

Esketamine Nasal Spray Market Share

Browse key industry insights with market data tables & charts from the report:

Frequently Asked Questions (FAQ)

In the year 2026, the industry size of esketamine nasal spray is estimated at USD 28.77 billion.

The global esketamine nasal spray market size crossed USD 27.11 billion in 2025 and is likely to register a CAGR of over 6.8%, exceeding USD 52.34 billion revenue by 2035.

North America is projected to secure a 38% share by 2035 in the esketamine nasal spray market, underpinned by the escalating prevalence of depression across the region.

Key players in the market include Eli Lilly & Company, Bristol Myers Squibb Company, Novartis International AG, Bausch Health Companies Inc., Validus Pharmaceuticals LLC, Pfizer Inc., AbbVie Inc., Merck KGaA, Endo International Plc, MedKoo Biosciences, Inc., Janssen Global Services, LLC, Otsuka Pharmaceutical Co., Ltd., Biogen Inc., Sage Therapeutics, Inc.
Inquiry Before Buying Request Free Sample PDF
footer-bottom-logos