DNA Synthesis Market Trends

Growth Drivers

• Precision and scalability offered by CRISPR-Cas9: CRISPR-Cas9 is one of the most powerful tools, which is helping researchers in gene editing and molecular biology. It offers automation and standardization to genetic engineering. This advanced CRISPR-Cas9 gene editing tool’s application in DNA synthesis leads to near-perfect accuracy and precision in DNA design. Also, CRISPR-Cas9’s increasing demand in research and clinical settings for swift and scalable DNA synthesis solutions is contributing to the overall DNA synthesis market growth. Some key market players are launching advanced CRISPR solutions to enhance experiment time and results. For instance, in June 2021, QIAGEN, N.V. announced the launch of QIAprep& CRISPR Kit and CRISPR Q-Primer Solutions. These CRISPR products are aiding researchers in rapid and simplified analysis of gene editing experiments.
• DNA synthesis in agriculture: The increasing demand for engineered plants underscores the rising applications of DNA synthesis in the agricultural sector. The advancements in biology and DNA synthesis are driving the production of custom-designed plants, which aids in improving agricultural productivity. The role of DNA synthesis is to design crops with beneficial traits that increase crop yields, reduce the risks of infestation, and mitigate the need for chemical fertilizer for growth. Thus, the introduction of DNA synthesis in engineered plant production is highlighting the move towards and adoption of modern agriculture practices, which meet the needs of both farmers and consumers.

Challenges

• Lengthy and complex approval procedures: The long approval procedures, coupled with a lack of standardization are hindering the DNA synthesis market growth. The regulatory uncertainties and lengthy product approval processes are limiting the entry of new synthesized DNA solutions, leading to huge profit losses for market players. For instance, in July 2024, the European Medicine Agency released new regulations for the development and manufacturing of oligonucleotides. Such changes in regulations also create confusion at the manufacturers’ end, leading to slow product launches and loss of trending opportunities.
• High cost of advanced DNA synthesis technologies: Advanced DNA synthesis technologies are costly and complex, which limits their adoption to some extent. Researchers or end use organizations working on limited budgets often find it difficult to invest in advanced DNA synthesis tools, creating barriers before both users and manufacturers. Budget-constraint end users remain inaccessible to advanced DNA synthesis technologies and manufacturers face challenges in revenue growth.