Chronic Ocular Surface Pain Market Size & Share, by Route of Administration (Topical, Oral, Injectable); Indication; Treatment Type - Global Supply & Demand Analysis, Growth Forecasts, Statistics Report 2025-2037

  • Report ID: 7101
  • Published Date: Feb 06, 2025
  • Report Format: PDF, PPT

Global Market Size, Forecast, and Trend Highlights Over 2025-2037

Chronic Ocular Surface Pain Market size was valued at USD 15.3 billion in 2024 and is anticipated to surpass USD 31.1 billion by 2037, registering a CAGR of 6.1% during the forecast timeline i.e. 2025-2037. In 2025, the industry size of chronic ocular surface pain is estimated at USD 16.2 billion.

The chronic ocular surface pain market is flourishing due to the increasing elderly population. For instance, in October 2024, statistics revealed by WHO stated that there were 1.4 billion people over the age of 60, up from 1 billion in 2020. The number of people in the world who are 60 years of age or older is expected to double to 2.1 billion by 2050. Between 2020 and 2050, the population of people 80 years of age or older is predicted to triple, reaching 426 million. Thus, aging causes the accumulation of numerous types of cellular and molecular damage over time.

In addition, growth in lifestyle factors, and increased screen time are contributing to conditions of dryness and stress that cause environmental conditions will also worsen dry eye symptoms. For instance, in October 2024, statistics published by the Centers for Disease Control and Prevention, about one-half of teenagers had 4 hours or more of daily screen time. From July 2021 through December 2023, 50.4% of teenagers ages 12 to 17 had 4 hours or more of daily screen time, 22.8% had 3 hours, 17.8% had 2 hours, 6.1% had 1 hour, and 3.0% had less than 1 hour of daily screen time resulting in eye disorders.

There is an increasing recognition by health professionals of the spectrum of ocular pain syndromes. As recently developed trends indicate, there is a paradigm shift to more holistic diagnostic methodologies, which embrace advanced imaging techniques such as optical coherence tomography and functional assessments to better understand the health of the ocular surface. Furthermore, with increasing awareness within clinical and research circles, chronic ocular surface pain has emerged as an important priority to further improve care in ophthalmic settings.


Chronic Ocular Surface Pain Market
Get more information on this report: Request Free Sample PDF

Chronic Ocular Surface Pain Sector: Growth Drivers and Challenges

Growth Drivers

  • Rising prevalence of dry eyes: The chronic ocular surface pain market is characterized by dry eye disease, other forms of surface disorder, or the presence of a neuropathic pain mechanism. For instance, in January 2023, according to the data unveiled by the National Library of Medicine, the prevalence of Dry Eye Disease (DED) varied between 5% and 50% worldwide. Additionally, postmenopausal women have been more likely to have the condition. Throughout the forecast period, this trend will raise the demand for therapeutic measures and support the expansion of the global market.

    In addition to this, as people age, the prevalence of this chronic condition changes. Nonetheless, the prevalence is rising among both the younger and older populations as a result of increased screen time, poor diet, contact lens use, and LASIK procedures. For instance, in April 2023, around 36-75% suffer from dry eyes post-LASIK. As it affects a significant portion of the population, dry eye syndrome has one of the highest overall burdens in terms of healthcare services and costs.
     
  • Personalized medication approaches: A pivotal growth driver in the chronic ocular surface pain market is reflected by the shift towards treatment strategies based on the individual needs of patients. For instance, in May 2024, Johnson & Johnson announced two oral research presentations at the Association for Research in Vision and Ophthalmology (ARVO) 2024 Annual Meeting in Seattle. This included a real-world analysis of the economic value of early genetic testing in patients with inherited retinal diseases and evaluating the role of automatic deep-learning-based algorithms in measuring precursors of geographic atrophy (GA).

    Furthermore, an individualized approach not only strengthens the effectiveness of treatment but also reduces side effects, thereby supporting improved compliance and adherence by the patient. For instance, in April 2022, Sandoz revealed the US launch of its generic combination eyedrop brimonidine tartrate/timolol maleate ophthalmic solution 0.2%/0.5%. This is intended to help patients with ocular hypertension (high eye pressure) lower their eye pressure. Consequently, as the market for precision medicine is growing, the chronic ocular surface pain market is expected to boom considerably with innovations aimed toward optimal clinical outcomes.

Challenges

  • Underappreciation of eye health monitoring:  The general public's perception of eye health is one of the key factors preventing the chronic ocular surface pain market from expanding. Except in cases of severe symptoms, people do not regularly visit ophthalmologists. Redness, burning, and other symptoms of dry eyes are frequently disregarded and go undiagnosed. For instance, an estimated 5 million people in the UK have never had an eye test, according to a survey released in March 2022 by the Broadgreen University Hospital NHS Trust.

    In addition, according to the data published in National Eye Health Week, in September 2024, the population estimated using the total UK population aged 18+ is 56.3 million. 36% have not had an eye test in the last two years, and 4% can’t remember the last time they had an eye test. As a result, fewer patients are eligible to receive treatment with these prescription medications. As a result, the market's potential for growth is constrained and the adoption rate of these eye care products declines.
     
  • Healthcare access barrier: The most significant challenge in the chronic ocular surface pain market is the prohibition of proper management of chronic ocular surface pain. As a result, fewer patients are eligible to receive treatment with these prescription medications. As a result, the market's potential for growth is constrained and the adoption rate of these eye care products declines. Patients often face obstacles such as inadequate availability of specialized care, high treatment costs, and limited insurance coverage for advanced therapies.

    These factors contribute to delays in diagnosis and treatment, exacerbating patient suffering and diminishing quality of life. These barriers are therefore important in ensuring that there is an improvement in patient outcomes as well as fair access to appropriate interventions in ocular health.

Base Year

2024

Forecast Year

2025-2037

CAGR

6.1%

Base Year Market Size (2024)

USD 15.3 billion

Forecast Year Market Size (2037)

USD 31.1 billion

Regional Scope

  • North America (U.S., and Canada)
  • Asia Pacific (Japan, China, India, Indonesia, Malaysia, Australia, South Korea, Rest of Asia Pacific)
  • Europe (UK, Germany, France, Italy, Spain, Russia, NORDIC, Rest of Europe)
  • Latin America (Mexico, Argentina, Brazil, Rest of Latin America)
  • Middle East and Africa (Israel, GCC North Africa, South Africa, Rest of the Middle East and Africa)

Get more information on this report: Request Free Sample PDF

Chronic Ocular Surface Pain Segmentation

Treatment Type (Artificial Tears, Oral Medications, Surgery, Topical Antibiotics, Anti-inflammatory Eye Drops)

The artificial tears segment is set to account for around 45% chronic ocular surface pain market share by 2037. For instance, Cleveland Clinic revealed statistics stating, that approximately 90% of patients with mild or moderate ocular pain reported that artificial tears improved their symptoms, whereas 53% of patients with severe pain reported improvement. In addition, people accept this most as the pain reliever associated with chronic ocular surface. For instance, in March 2024, Formosa Pharmaceuticals and AimMax Therapeutics unveiled that, Eyenovia's APP13007 eye drops have received FDA approval for the treatment of pain and inflammation following ocular surgery.

Route of Administration (Topical, Oral, Injectable)

The topical medications segment is anticipated to dominate the chronic ocular surface pain market by 2037 because it is applied topically and impacts the ocular surface locally. This route of administration provides prompt relief of symptoms while limiting systemic side effects and tends to remain a health provider's and patient's preferred choice. For instance, in January 2024, Alcon reported that the two pivotal Phase 3 clinical trials (COMET-2 and COMET-3) assessed the safety and effectiveness of AR-15512. It is a potential treatment for the symptoms and indicators of dry eye disease (DED), producing positive topline results.

Our in-depth analysis of the global chronic ocular surface pain market includes the following segments:

Treatment Type

  • Artificial Tears
  • Surgery
  • Topical Antibiotics
  • Oral Medications
  • Anti-inflammatory Eye Drops

Indication

  • Dry Eye Disease
  • Stevens-Johnson Syndrome
  • Sjgren's Syndrome
  • Pterygium
  • Contact Lens Intolerance

Route of Administration

  • Topical
  • Oral
  • Injectable

 


Want to customize this research report as per your requirements? Our research team will cover the information you require to help you take effective business decisions.

Customize this Report

Chronic Ocular Surface Pain Industry - Regional Synopsis

North America Market Statistics   

North America chronic ocular surface pain market is expected to capture revenue share of over 34.4% by 2037. The presence of technologically advanced giants, innovators, assisting regulatory bodies, and researchers eases the process of introducing revolution in the field.  For instance, in June 2023, Novaliq GmbH announced that VEVYETM 0.1% has been approved by the U.S. FDA to treat the indicators of dry eye disease. With efficacy shown after 4 weeks of treatment, VEVYETM is the first and only cyclosporine solution recommended for the treatment.

In the U.S. Chronic ocular surface pain market is expanding its footprints through the strong support from regulatory bodies that bolster the development and adoption of novel drugs. For instance, in October 2021, Allergan announced that VUITYTM 1.25% had received FDA approval for the treatment of presbyopia. VUITY is the first and only FDA-approved eye drop for this common and progressive eye condition, which affects 128 million Americans, or nearly half of the nation's adult population.

Canada chronic ocular surface pain market is rapidly growing due to acquisitions and mergers between companies. For instance, in June 2023, Bausch + Lomb had agreed to take up Novartis’s front-of-eye ophthalmology assets for up to USD 2.5 billion.  Xiidra, the first approved prescription treatment for the signs and symptoms of dry eye disease, the rights to use the AcuStream delivery device in dry eye indications, and OJL332, a second-generation TRPV1 antagonist in pre-clinical development, are all included in the deal.

Asia Pacific Market Analysis

The chronic ocular surface pain market in Asia Pacific is gaining traction and is expected to witness lucrative growth during the forecast timeline i.e. 2025-2037. The growth is attributable to the discoveries of novel therapeutic drugs. For instance, in September 2022, the results of TearSolutions' first-in-human study on its pipeline candidate Lacripep, which is prescribed to treat dry eye disease, were positive. It is a potentially revolutionary treatment for Dry Eye Disease (DED), and has been published in Cornea, a prestigious peer-reviewed ophthalmology journal.

India chronic ocular surface pain market is growing substantially owing to the advancing ecosystem in the field of biologics. For instance, in January 2025, India made a massive advancement in genomics by launching, Indian Genomic Data Set and IBDC Portals to support international research. It is a huge accomplishment that will spur more advancements in science and medicine. The 10,000 whole genome samples that have been archived at IBDC are now accessible for research purposes both domestically in India and internationally. For genomics research, this data set will be an invaluable asset, advancing personalized medicine and healthcare.

China chronic ocular surface pain market is growing at a steady pace attributable to the altruist moves to help its population with a cure. For instance, in January 2025, in the Ethiopian capital of Addis Ababa, a China medical team from Tianjin Eye Hospital formally began a free cataract surgery campaign at Tirunesh Beijing Hospital. With 80 of them having already experienced successful procedures, the China medical team, which consists of 10 senior ophthalmologists and nurses, is scheduled to perform cataract surgery for over 500 eye patients under the China-Ethiopia Brightness Journey name.

Chronic Ocular Surface Pain Market Share
Get more information on this report: Request Free Sample PDF

Companies Dominating the Chronic Ocular Surface Pain Landscape

    The companies in the chronic ocular surface pain market are expanding their portfolio and focusing on gaining expertise in the field through leveraging proficiency in treatments and rendering exclusive rights. For instance, in May 2024, with an initial payment of USD 1.3 billion and potential milestone payments of up to USD 1.7 billion, Merck purchased EyeBio for a total of USD 3 billion. With this acquisition, Merck will keep expanding and diversifying the pipeline as part of its science-led business development strategy.

    Here's the list of some key players:

    • Novartis International AG
      • Company Overview
      • Business Strategy
      • Key Product Offerings
      • Financial Performance
      • Key Performance Indicators
      • Risk Analysis
      • Recent Development
      • Regional Presence
      • SWOT Analysis
    • Shire, Mimetogen Pharmaceuticals
    • Kala Pharmaceuticals
    • Presbia
    • Theratechnologies
    • Ocular Therapeutix
    • Bausch + Lomb
    • Dompé
    • Oyster Point Pharma
    • EyeGate Pharmaceuticals
    • TearScience
    • Xintela
    • Allergan plc

In the News

  • In January 2024, Alcon reported encouraging outcomes from Phase 3 clinical trials (COMET-2 and COMET-3) for the treatment of dry eye disease.
  • In May 2022, Kala Pharmaceuticals, Inc. agreed to sell EYSUVIS (loteprednol etabonate suspension) 0.25% pharmaceutical eye drops to Alcon.
    The purchase enhanced Alcon's line of business in the sizable and rapidly expanding dry eye market.

Author Credits:   Radhika Pawar


  • Report ID: 7101
  • Published Date: Feb 06, 2025
  • Report Format: PDF, PPT

Frequently Asked Questions (FAQ)

In the year 2024, the industry size of the Chronic ocular surface pain market was over USD 15.3 billion.

The market size for the Chronic ocular surface pain market is projected to reach USD 31.1 billion by the end of 2037 expanding at a CAGR of 6.1% during the forecast period i.e., between 2025-2037.

The major players in the market are Oyster Point Pharma, EyeGate Pharmaceuticals, TearScience, Xintela, Allergan plc, and more.

In terms of treatment type, the artificial tears segment is anticipated to garner the largest market share of 45.0% by 2037 and display lucrative growth opportunities during 2025-2037.

The market in North America is projected to account for a prominent share of 34.4% by the end of 2037 and provide more business opportunities in the future.
logo
GET A FREE SAMPLE

FREE Sample Copy includes market overview, growth trends, statistical charts & tables, forecast estimates, and much more.

 Request Free Sample Copy

See our insights in action - schedule your demo now!

Live Sample Reading