Choroideremia Treatment Market Size & Share, by Therapy (Topical Carbonic Inhibitor, Dorzolamide, Gene Therapy, Luxturna, Lutein); Route of Administration (Oral, Intravenous, Ophthalmic); Distribution Channel (Hospital Pharmacies, Retail Pharmacies, Drugstores, Online Pharmacies) - Global Supply & Demand Analysis, Growth Forecasts, Statistics Report 2024-2036

  • Report ID: 5519
  • Published Date: May 09, 2024
  • Report Format: PDF, PPT

Global Market Size, Forecast, and Trend Highlights Over 2024-2036

Choroideremia Treatment Market size is estimated to reach USD 33 billion by the end of 2036, expanding around 5% CAGR during the forecast period i.e., 2024-2036. In the year 2023, the industry size of choroideremia treatment was over USD 9 billion.

 The growth of this market can be ascribed to the increasing prevalence of choroideremia all across the globe. 1 in 50,000 to 100,000 people in the United States has choroideremia according to the Centers for Disease Control and Prevention.

Due to the delay in diagnosis and treatment of patients with choroideremia, COVID-19 is likely to have an important effect on the therapeutic market for choroideremia. Anyhow, the result will be short-term and post-COVID-19 pandemic, the choroideremia treatment market will show a significant surge owing to an increase in treatment adoption.


Choroideremia Treatment Market
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Choroideremia Treatment Sector: Growth Drivers and Challenges

Growth Drivers

  • Growing advancement in medical technology - One of the main factors propelling the market for choroideremia treatments is advancements in healthcare technologies. Numerous advancements over the past several years have resulted in novel choroideremia therapy options. 

    These advancements not only expanded the pool of treatments available but also improved accessibility to them. Patients can now better manage their symptoms and improve their quality of life because of the medications' increased efficacy.
     
  • Favorable government policies - Globally, governments are becoming more proactive in fostering the development and availability of treatments for rare diseases such as choroideremia. Patients now have more access to medicines and treatments that can help regulate their symptoms as a result of this assistance, which has also stimulated innovation and investment in the field.

Challenges

  • Complex disease pathology - Choroideremia is caused by mutations in the CHM gene that affect the production of a protein essential for the proper function of the retina. The complex interplay between genetics, cellular processes, and visual function makes it challenging to develop effective therapies.
  • Side effects and safety issues associated with the treatment.
  • Limited access to specialty is another factor posing limitations on the choroideremia treatment market growth in the near future.

Choroideremia Treatment Market: Key Insights

Base Year

2023

Forecast Year

2024 - 2036

CAGR

5%

Base Year Market Size (2023)

USD 9 billion

Forecast Year Market Size (2036)

USD 33 billion

Regional Scope

  • North America (U.S., and Canada)
  • Latin America (Mexico, Argentina, Rest of Latin America)
  • Asia-Pacific (Japan, China, India, Indonesia, Malaysia, Australia, Rest of Asia-Pacific)
  • Europe (U.K., Germany, France, Italy, Spain, Russia, NORDIC, Rest of Europe)
  • Middle East and Africa (Israel, GCC North Africa, South Africa, Rest of the Middle East and Africa)
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Choroideremia Treatment Segmentation

Route of Administration (Oral, Intravenous, Ophthalmic)

In choroideremia treatment market, ophthalmic segment is likely to account for around 40% share by 2036. The growth of this segment can be attributed on account of increasing integration of gene therapy in ophthalmic route of administration.

Gene therapy is regarded as a promising approach for treating choroideremia and its adoption is anticipated to rise in the upcoming years. This is owing to factors such as enhanced safety and efficacy profiles of gene therapy vectors and increasing clinical trial data supporting its effectiveness. Biogen Inc. initiated a Phase 3 STAR study of timrepigene emparvovec (BIIB111/AAV2-REP1), an investigational gene therapy for the potential treatment of choroideremia.

Distribution Channel (Hospital Pharmacies, Retail Pharmacies, Drugstores, Online Pharmacies)

In choroideremia treatment market, hospital pharmacies segment is predicted to hold more than 40% revenue share by 2036. Hospital pharmacies often serve as the central distribution point for specialized and high-cost medications such as those targeted for rare diseases like choroideremia.

This efficiency in supply chain management could benefit patients by ensuring timely access to treatment. Furthermore, as new choroideremia treatments especially gene therapy approaches reach the market, innovative reimbursement pathways are being explored. Hospital pharmacies are likely to play a crucial role in navigating these play a key role in navigating these reimbursement complexities and facilitating patient access to treatment.

Our in-depth analysis of the global choroideremia treatment market includes the following segments:  

          Therapy

  • Topical Carbonic Inhibitor
  • Dorzolamide
  •  Gene Therapy
  •  Luxturna
  • Lutein

          Administration

  • Oral
  • Intravenous
  • Ophthalmic

          Distribution Channel

  • Hospital Pharmacies
  •  Retail Pharmacies
  •  Drugstores
  • Online Pharmacies

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Choroideremia Treatment Industry - Regional Synopsis

North American Market Forecast

By 2036, North America region is projected to account for around 35% choroideremia treatment market share. North America is an epicenter of innovation and technology that has helped the region establish itself as a leader in the healthcare industry.

This is also true for the market for choroideremia treatments in North America, where developments in R&D are propelling the industry to new heights. A number of clinical centres that focus on the diagnosis and treatment of choroideremia could potentially account for the growth. Numerous services are provided by these centres, including genetic testing, rehabilitation for individuals with limited vision, and access to experimental medications like gene therapy.

For occasion, the Choroideremia Inquire about Establishment CRFC is a nongovernmental organization committed to financing and investigating on potential medications and cures for Choroideremia in Canada

APAC Market Statistics

The market in the Asia Pacific region is predicted to grow significantly by the end of 2036. The Asia Pacific region is experiencing rapid economic growth leading to escalating disposable incomes in many countries. This makes patients more willing and able to afford costly choroideremia treatments.

Governments in the region are also investing highly in infrastructure, making advanced treatments more accessible to patients. Furthermore, recent advancements in gene therapy and optogenetics hold promise for the development of more effective treatments for choroideremia. Several clinical trials are currently underway in the Asia Pacific region for novel therapies that could boost growth of the choroideremia treatment market in the future.

Research Nester
Choroideremia Treatment Market Size
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Companies Dominating the Choroideremia Treatment Landscape

    • Novartis AG
    • Spark Therapeutics
    • Bluebird Bio Inc.
    • Biogen Inc.
    • Copernicus Therapeutics, Inc.
    • 4D Molecular Therapeutics
    • Wize Pharma Inc.
    • Retina Implant AG
    • Hoffmann-La Roche Ltd
    • Kiora Pharmaceuticals
    • Astellas Pharma Inc.
    • Pixium Vision

In the News

  • Biogen Inc., announced that the final patient has been enrolled in the international Phase 3 STAR clinical trial evaluating timrepigen-emparvovec, an experimental gene therapy for the treatment of choroideremia.
  • Astellas Pharma and 4D Molecular Therapeutics, Inc. acquire rights for Astellas to use the R100* intravitreal retinotropic vector invented by 4DMT for gene targets involved in rare monogenic eye diseases Announced license agreement (with option to add up to two additional targets) for an additional option exercise fee, potentially implicating rare monogenic eye diseases. R100 is a vector invented by 4DMT for intravitreally delivery of the adeno-associated virus, AAV. It's capable of breaking into the internal membrane wall and effectively transducing the whole retina, resulting in a strong gene expression for retinal cells. The R100 vector is used, including 4D-150 in wet agerelated macular degeneration and diabetic macular edema, by all the three clinical stage4DMT ophthalmic product candidates.

Author Credits:  Radhika Pawar


  • Report ID: 5519
  • Published Date: May 09, 2024
  • Report Format: PDF, PPT

Frequently Asked Questions (FAQ)

The growing prevalence of choroideremia and growing advancement in medical technology are some of the major factors anticipated to drive the growth of the choroideremia treatment market.

The market is anticipated to attain a CAGR of ~5% over the forecast period, i.e., 2024-2036.

The major players in the market are of Biogen, Copernicus Therapeutics, Inc., 4D Molecular Therapeutics, Wize Pharma Inc., Retina Implant AG, Hoffmann-La Roche Ltd, and others.

The ophthalmic segment is anticipated to garner the largest market size by the end of 2036 and display significant growth opportunities.

The market in North America is projected to hold the largest market share by the end of 2036 and provide more business opportunities in the future.
Choroideremia Treatment Market Report Scope
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