Cementless Total Knee Arthroplasty Market size was over USD 2.67 billion in 2024 and is projected to reach USD 5.98 billion by 2037, growing at around 6.4% CAGR during the forecast period i.e., between 2025-2037. In the year 2025, the industry size of cementless total knee arthroplasty is evaluated at USD 2.81 billion. The rising prevalence of knee osteoarthritis is one of the primary growth factors of the market. According to the Centers for Disease Control and Prevention (CDC) osteoarthritis affects more than 500 million which is about 7% of the world’s population.
The cementless total knee arthroplasty market refers to the medical devices and surgical procedures related to knee replacement surgeries that do not involve the use of bone cement to secure the artificial components in the patient's knee joint. Cementless TKA is an alternative approach to traditional knee replacement surgery, where bone cement is used to fix the prosthesis in place. Cementless TKA has gained popularity for several reasons, including its potential to provide better long-term implant stability and reduce the risk of complications associated with cemented TKA. Ongoing research and clinical studies are conducted to assess the long-term outcomes and benefits of cementless TKA. This research informs clinical practice and helps in the development of improved implant designs.
Growth Drivers
Challenges
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Base Year |
2024 |
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Forecast Year |
2025-2037 |
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CAGR |
6.4% |
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Base Year Market Size (2024) |
USD 2.67 billion |
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Forecast Year Market Size (2037) |
USD 5.98 billion |
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Regional Scope |
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Type (Primary, Revision)
The primary cementless TKA segment is estimated to hold 60% share of the global cementless total knee arthroplasty market in the year 2037. The global primary cementless TKA segment is experiencing substantial growth due to a combination of demographic changes, lifestyle factors, technological advancements, patient awareness, surgeon preferences, market competition, regulatory oversight, and ongoing innovation. These factors collectively contribute to the expansion of primary cementless TKA as a preferred solution for addressing knee joint problems and enhancing the quality of life for patients worldwide.
Stringent regulatory requirements for medical devices exist in many countries to ensure the safety and efficacy of cementless TKA implants. A robust regulatory framework fosters trust among surgeons, patients, and healthcare systems. This trust, in turn, contributes to the growth of the global primary cementless TKA market. Information about regulatory frameworks and approvals for medical devices can be obtained from the websites of relevant regulatory agencies in different countries. For example, the Food and Drug Administration (FDA) in the United States and the European Medicines Agency (EMA) in Europe provide information on regulatory requirements and approvals.
End User (Hospitals, Home Healthcare, Ambulatory Surgery Centers)
Cementless total knee arthroplasty market from the hospitals segment is expected to garner a significant share in the year 2037. Osteoarthritis is a leading indication for primary cementless TKA procedures, and its prevalence is rising. This condition results in pain, reduced mobility, and functional limitations, leading to a greater demand for surgical interventions in hospital settings. The World Health Organization (WHO) reports that osteoarthritis is the most common form of arthritis and is a significant cause of pain and disability worldwide. As the prevalence of osteoarthritis continues to increase, the demand for primary cementless TKA procedures in hospitals grows accordingly. Rehabilitation is an integral part of the recovery process for patients undergoing primary cementless TKA. Hospitals are equipped to provide comprehensive rehabilitation services, including physical therapy, to help patients regain mobility and function after surgery. The availability of these services contributes to the success of primary cementless TKA in hospital settings.
Our in-depth analysis of the global market includes the following segments:
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Type |
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End User |
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APAC Market Forecast
The cementless total knee arthroplasty market in the Asia Pacific industry is set to account for largest revenue share of 38% by 2037. The cementless TKA market in the Asia Pacific region is experiencing significant growth due to a combination of demographic changes, lifestyle factors, technological advancements, surgeon expertise, patient awareness, regulatory compliance, and the availability of specialized orthopedic centers. These drivers collectively contribute to the success of cementless TKA as a preferred solution for addressing knee joint problems and improving the quality of life for patients in the Asia Pacific region.
Specialized orthopedic centers and hospitals in the Asia Pacific region provide focused care for joint-related conditions, including cementless TKA. The presence of these centers ensures that patients have access to specialized expertise and advanced surgical techniques. Reports and publications on healthcare infrastructure in Asia Pacific countries often highlight the role of specialized orthopedic centers in addressing joint conditions and performing joint replacement procedures. These centers are significant drivers for the growth of cementless TKA in the region.
North American Market Statistics
The cementless total knee arthroplasty market in the North America region is projected to hold the second largest share during the forecast period. Continuous advancements in implant design, materials, and surgical techniques have significantly improved the success and longevity of cementless TKA in North America. Innovative materials, such as highly cross-linked polyethylene and advanced metal alloys, have reduced wear rates, enhanced implant stability, and extended implant lifespan. Information about the latest advancements in cementless TKA implants and technologies is often published in academic journals, industry reports, and on the websites of leading medical device manufacturers. These innovations have had a substantial impact on the success of cementless TKA procedures in North America. Obesity is a significant risk factor for osteoarthritis and knee joint problems, making it a noteworthy growth driver in North America. The region has seen an increase in obesity rates due to changes in lifestyle, which contributes to the need for joint replacement procedures, including cementless TKA. The CDC and Health Canada provide data on obesity rates and their implications for public health in North America. According to the Centers for Disease Control and Prevention (CDC), in the United States, the prevalence of obesity has been steadily increasing over the years. In 2019-2020, the age-adjusted prevalence of obesity among adults was approximately 42.4%. This means that almost 4 out of 10 adults in the U.S. were considered obese.
Author Credits: Radhika Pawar
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