Catheter-Directed Thrombolysis Market Analysis

  • Report ID: 4220
  • Published Date: Sep 24, 2025
  • Report Format: PDF, PPT

Catheter-Directed Thrombolysis Market Segmentation:

Route of Administration Segment Analysis

Under the route of administration segment, vascular access leads the segment and is poised to hold the share value of 85% by 2035. The dominance is encompassed by the treatment of conditions in the peripheral vasculature, primarily Deep Vein Thrombosis (DVT) and Peripheral Arterial Occlusion. More than one-third of VTE cases require hospital care, and the majority involve DVT in the peripheral vessels, based on the CDC report in January 2025. The patient pool for these conditions is vastly larger than for neurovascular cases. Procedures for iliofemoral DVT, for example, are a primary growth driver for the entire CDT market. The high prevalence of venous thromboembolism, as documented by the CDC, ensures that vascular access remains the predominant route of administration, requiring a wide range of catheters designed for navigation in larger peripheral veins and arteries.

End user Segment Analysis

Hospitals are fueling the end user segment and will be expected to hold significant share value by 2035. Hospitals serve a significant role in CDT procedures because of the complex infrastructure requirements, high cost of equipment, and immediate access to multidisciplinary care teams. CDT is an acute care procedure typically performed in either emergency room settings or on hospital patients. It requires advanced imaging suites, critical care support to monitor potential incidents such as bleeding, and the presence of specialist interventional radiologists or cardiologists.

Drug Type Segment Analysis

Tissue plasminogen activator is leading the drug segment and remains as the pharmacological gold standard based on its high fibrin specificity and strong clinical history. The NLM report in August 2025 depicts that alteplase has a safety profile of a standard drug, with symptomatic intracranial hemorrhage occurring in about 8% of acute ischemic stroke patients treated, consistent across multiple clinical trials. Its dominance is supported by its status as the primary agent studied in major clinical trials and its inclusion in treatment guidelines. While other drugs like urokinase are used, tPA's efficacy and the clinical familiarity established through its use in ischemic stroke protocols solidify its position. Regulatory approvals for CDT devices and treatment protocols are most commonly referenced for use with tPA, making it the first-choice agent for clinicians.

Our in-depth analysis of the catheter-directed thrombolysis market includes the following segments:  

Segment

Subsegments

Product

  • Ultrasound-Assisted Thrombolysis Systems
  • Deep Vein Thrombosis (DVT)
  • Pulmonary Embolism (PE)
  • Peripheral Arterial Occlusion
  • Arterial Thrombosis
  • Other Applications
  • Standard Infusion Catheter Systems
  • Deep Vein Thrombosis (DVT)
  • Pulmonary Embolism (PE)
  • Peripheral Arterial Occlusion
  • Arterial Thrombosis
  • Other Applications
  • Thrombolytic Drugs
  • Deep Vein Thrombosis (DVT)
  • Pulmonary Embolism (PE)
  • Peripheral Arterial Occlusion
  • Arterial Thrombosis
  • Other Applications

Application

  • Deep Vein Thrombosis (DVT)
  • Pulmonary Embolism (PE)
  • Peripheral Arterial Occlusion
  • Arterial Thrombosis
  • Other Applications

Drug Type

  • Tissue Plasminogen Activator (tPA)
  • Urokinase
  • Streptokinase
  • Other Drugs

End user

  • Hospitals
  • Tissue Plasminogen Activator (tPA)
  • Urokinase
  • Streptokinase
  • Other Drugs
  • Ambulatory Surgical Centers
  • Tissue Plasminogen Activator (tPA)
  • Urokinase
  • Streptokinase
  • Other Drugs
  • Specialty Clinics
  • Tissue Plasminogen Activator (tPA)
  • Urokinase
  • Streptokinase
  • Other Drugs

Route of Administration

  • Vascular Access
  • Neurovascular Access

Browse key industry insights with market data tables & charts from the report:

Frequently Asked Questions (FAQ)

In the year 2025, the industry size of catheter-directed thrombolysis is evaluated at USD 510.6 million.

Catheter-Directed Thrombolysis Market size was valued at USD 510.6 million in 2025 and is projected to reach USD 573.6 million by the end of 2035, growing at a CAGR of 6% during the forecast period 2026-2035.

The North America catheter-directed thrombolysis market is anticipated to grow steadily and is expected to have a market share of 40% by 2035.

The major players in the market are Medtronic plc, Boston Scientific Corporation, Penumbra Inc., Becton, Dickinson and Company, Cook Medical, Terumo Corporation, Philips Healthcare, Stryker Corporation, Teleflex Inc., AngioDynamics Inc., MicroPort Scientific, Acotec Scientific, Meril Life Sciences, Nipro Corporation.
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