Antibody Purification Services Market size is expected to reach a USD 3 Billion by the end of 2036, growing at a CAGR of 12% during the forecast period, i.e., 2024-2036. In the year 2023, the industry size of antibody purification services was USD 1 Billion. The increasing number of cases of chronic diseases across the world will exponentially help the market to grow in the expected CAGR. WHO stated that even though the overall health problem is in a better place now, the rising burden of non-communicable diseases (NCDs) may impact massively on the world. If current trends of chronic diseases continue, by approximately 2050, chronic illnesses like cancer, diabetes, cardiovascular disease, and respiratory disorders will be responsible for 86% i.e. around 90 million deaths annually; this represents a startling 90% increase in absolute numbers since 2019.
Another reason to propel the antibody purification services market by the end of 2036 is the rising use of therapeutics to treat diseases globally. Presently, almost 4,000 uncommon diseases are not cured appropriately, and only 10% of rare diseases worldwide are treated appropriately. In China, where there are more than 1.4 billion people, there is a strong social need for drug research and solutions for rare diseases despite the low prevalence of these conditions. For instance, in modern medicine, gene therapy is at the forefront. These cutting-edge technologies have the potential to create one-time, permanent cures for infectious and non-communicable diseases (including HIV and sickle cell disease), which afflict tens of millions of people worldwide, the majority of whom reside in low- and middle-income countries (LMICs), by precisely altering the human genome. Although the gene therapy field is still in its infancy, significant funding and early clinical achievements have given it a lot of momentum.
Growth Drivers
Challenges
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Base Year |
2023 |
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Forecast Year |
2024-2036 |
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CAGR |
∼12% |
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Base Year Market Size (2023) |
~USD 1 Billion |
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Forecast Year Market Size (2036) |
~USD 3 Billion |
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Regional Scope |
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Type (Physiochemical Fractionation, Class-Specific Affinity, Antigen-Specific Affinity)
The antigen-specific affinity segment is expected to hold around 47% share of the global antibody purification services market by 2036.because of the rising demand for antigen-specific affinity in various applications. Based on the interaction between particular immobilized ligands and target antibodies, antigens, and so forth, affinity chromatography is an effective approach for separating antibodies, antigens, and proteins. Antibodies or their Fab fragments can be separated using populations of available ligands. Immunoaffinity chromatography (IAC) on low-affinity immobilized antibodies can also be used to isolate antigens. The natural affinity proteins of bacteria, like pA and pG, were the most often utilized when IgG affinity proteins were first created for use in antibody purification. Macromolecules and antibodies have a molecular weight of about 150 kDa. Antigen-binding fragment (Fab) and crystallizable fragment (Fc) combine to produce an antibody molecule, which has a "Y" shape.
Antibody Type (Monoclonal Antibodies, Polyclonal Antibodies, Recombinant Antibodies)
The monoclonal antibodies segment is expected to hold around 74% share of the global antibody purification services market by 2036 owing to the increasing financing on the research on monoclonal antibodies to create new therapeutics across the world. 2019 saw mAbs for inflammatory and cancerous conditions account for seven of the ten best-selling new medications. The US, Europe, and Canada account for 80% of the global market for mAb sales. 85% of the world's population lives in the rest of the world, while just 20% of mAbs are sold. Products containing monoclonal antibodies have emerged from relative obscurity in the 1990s to a position where they increasingly control patient impact and revenue creation. The past 20 years have seen a significant portion of this accomplishment, and we have pinpointed elements linked to the astounding developments that have aided in the identification, creation, and acceptance of monoclonal antibodies.
Our in-depth analysis of the global antibody purification services market includes the following segments:
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Type |
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Antibody Type |
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End-Use Industry |
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Service Type |
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Source |
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Application |
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North American Market Analysis
The antibody purification services market in the North America region will have the biggest growth during the forecast period with a revenue share of around 38%. This growth will be noticed owing to the increasing prevalence of cardiovascular diseases in this region. A study released recently in the Journal of the American College of Cardiology projects a considerable increase in the prevalence of cardiovascular risk factors and disease in the United States by the year 2060. Significant rises in cardiovascular trends underscore the need for fair access to preventive education and therapies now to avoid future disease and may put an increasing strain on the American healthcare system.
European Market Forecast
The antibody purification services market in the Europe region will also encounter huge growth during the forecast period, and hold the second position owing to the advancement in healthcare infrastructure in this region. Furthermore, care will be organized around the person by 2040 as opposed to the organizations that run the current healthcare systems. All stakeholders' businesses and operational models will be impacted by these changes, including newly established non-traditional healthcare companies. Since every European country oversees its healthcare system, the consequence is a patchwork of unique systems that are shaped by the unique political, economic, and cultural contexts of each country. Three main sources provide funding for healthcare: government programs, social health insurance (SHI), and private health insurance (PHI).
Author Credits: Radhika Pawar
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