Acinetobacter Pneumonia Therapeutics Market Size & Share, by Route of Administration (Parenteral, Oral, Inhalation); Distribution Channel, Drug Class; Age-Group - Global Supply & Demand Analysis, Growth Forecasts, Statistics Report 2025-2037

  • Report ID: 6546
  • Published Date: Oct 11, 2024
  • Report Format: PDF, PPT

Global Market Size, Forecast, and Trend Highlights Over 2025-2037

Acinetobacter Pneumonia Therapeutics Market size is evaluated at USD 496.9 million in 2024 and is projected to reach USD 1.1 billion by the end of 2037, growing at around 6.4% CAGR during the forecast period i.e., between 2025-2037. In 2025, the industry size of acinetobacter pneumonia therapeutics is estimated at USD 528.7 million.

The acinetobacter pneumonia therapeutics market growth trajectory is attributed to increasing prevalence of Acinetobacter pneumonia bacterial infection. According to a 2021 study on the prevalence of multidrug-resistant Acinetobacter baumannii, the prevalence of Acinetobacter baumannii was 3.37% and the overall mortality rate was 40.81%. The multi-drug resistance characteristics of these bacteria is increasing demands for advanced therapeutics options such as novel antibiotics, combination therapies, and antimicrobial peptides.

In June 2021, a report published in the National Library of Medicine (NLM) highlighted baumannii to be widespread in Asia and the U.S. For instance, in May 2023, the U.S. Food and Drug Administration (FDA) approved a new treatment for pneumonia induced by hospital-acquired bacterial pneumonia (HABP) and ventilator-associated bacterial pneumonia (VABP) called Xacduro. Growing government and private sector funding for antimicrobial resistance research is poised to fuel the acinetobacter pneumonia therapeutics market growth.

The World Health Organization (WHO) classifies Acinetobacter species on top of the list of critical bacterial pathogens that pose threats to human health, which pushes for a global need for advanced treatment and therapeutics. Additionally, COVID-19 pandemic highlighted the urgent need for effective treatment for Acinetobacter induced pneumonia cases which are on the rise. Healthcare systems across the world require novel solutions to risks posed by the Acinetobacter baumannii strain of bacteria. With rising investments in the healthcare sector and increasing research on bacterial strains, the global acinetobacter pneumonia therapeutics market is projected to maintain steady growth by the end of the forecast period.


Acinetobacter Pneumonia Therapeutics Market overview
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Acinetobacter Pneumonia Therapeutics Market Sector: Growth Drivers and Challenges

Growth Drivers

  • Increasing geriatric population and chronic diseases: The increasingly aging population globally with comorbidities and compromised immune systems puts them at risk of Acinetobacter pneumonia. The elderly population suffering from chronic health diseases result in a higher rate of hospital visits, increasing the risk of exposure to Acinetobacter baumannii. The World Population Prospects reports the population above 65 years of age is growing faster than the population below that and estimates the population above 65 to increase from 10% in 2022 to 16% in 2050.

    Aging exacerbates the risk of mortality in Acinetobacter pneumonia, and hence the demand for advanced therapeutic care is on the rise. The demographic shift globally is poised to fuel the growing demand for effective therapeutic solutions.
  • Rising prevalence of antibiotic resistant infections: The increasing prevalence of multi-drug resistant (MDR) Acinetobacter baumannii is a major driver of the acinetobacter pneumonia therapeutics market. For instance, in September 2024, research published in the Journal of Global Antimicrobial Resistance estimated an increase in Acinetobacter baumannii pneumonia cases to have increased between 2019 and 2023 along with the rate of carbapenem resistance. Rising cases of MDR A. baumannii have necessitated the demand for new antibiotics and combination therapies to assist the market’s growth.
  • Advancements in antimicrobial research: Advancements in antimicrobial research have enabled antibiotic discovery and the development of therapies to target Acinetobacter strains, assisting the robust growth of the acinetobacter pneumonia therapeutics market. Approval of new drugs such as Cefiderocol (Fetroja) is beneficial for the market’s growth as global and local players can invest in the distribution and manufacturing of the drug to cater to the growing demands for therapeutic care. For instance, in February 2024, Taiwan Shionogi & Co., Ltd., announced that Fetroja was approved by the Taiwan Food and Drug Administration (TFDA) for the treatment of hospital acquired pneumonia and other ailments.

Challenges

  • High cost of drug development and approval: Developing novel antibiotics for Acinetobacter pneumonia involves considerable investment in research and clinical trials. Additionally, there is no guarantee that the research will be successful, and hence pharmaceutical companies can face challenges allocating funds to research. Moreover, if the efficacy of a therapy is uncertain, then it may not be approved by the regulatory bodies, which can cause uncertain market returns. The time associated with research, clinical trials, approval, and then distribution of new therapeutics can be long, further affecting the market.
  • Lack of awareness and delayed diagnosis: The lack of awareness of hospital induced pneumonia, especially in emerging economies with an unreliable health ecosystem, can pose major challenges in treatment. Early identification is vital for treatment and the lack of diagnostic tools or expertise to detect antibiotic-resistance Acinetobacter can stymie the market growth and also dampen chances of expanding to new markets.

Acinetobacter Pneumonia Therapeutics Market: Key Insights

Base Year

2024

Forecast Year

2025-2037

CAGR

6.4%

Base Year Market Size (2024)

USD 496.9 million

Forecast Year Market Size (2037)

USD 1.1 billion

Regional Scope

  • North America (U.S., and Canada) 
  • Asia Pacific (Japan, China, India, Indonesia, Malaysia, Australia, South Korea, Rest of Asia-Pacific) 
  • Europe (UK, Germany, France, Italy, Spain, Russia, NORDIC, Rest of Europe) 
  • Latin America (Mexico, Argentina, Brazil, Rest of Latin America) 
  • Middle East and Africa (Israel, GCC North Africa, South Africa, Rest of the Middle East and Africa) 
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Acinetobacter Pneumonia Therapeutics Segmentation

Route of Administration (Parenteral, Oral, Inhalation)

The parenteral segment is set to capture around 73.5% acinetobacter pneumonia therapeutics market share by the end of 2037.  The segment’s rapid growth is owed to administrations of higher drug concentrations in severe Acinetobacter pneumonia cases. The method involves delivering medications directly to the bloodstream using intravenous (IV) or intramuscular (IM) injections, ensuring rapid drug absorption. In September 2019, the U.S. FDA approved Lefamulin that can be administered in oral and intravenous formulations to treat community acquired bacterial pneumonia. With the rising cases of MDR Acinetobacter strains, demand for IV antibiotics to quickly reach therapeutic levels in critically ill patients is driving the parenteral segment. For instance, in July 2024, Paratek Pharmaceuticals announced positive top-line efficacy from the postmarketing data of Nuzyra (Omadacycline) for patients with moderate to severe community-acquired bacterial pneumonia.

The oral segment in the treatment of Acinetobacter pneumonia is poised to increase its market share by the end of the forecast period. The segment’s growth is owed to ease of administration in moderate cases and in patients transitioning from home care to hospital care. Oral administration is comparatively more patient-friendly and reduces the requirements of an extended hospital stay. The development of new orally administered drug formulations to treat Acinetobacter pneumonia cases is poised to maintain the growth of the segment by cementing its position in early patient care. In December 2020, a study published in the National Library of Medicine highlighted new antibiotics for bacterial pneumonia to be administered orally such as omadacycline, solithromycin, and lefamulin.

Distribution Channel (Hospital Pharmacies, Retail Pharmacies, Online Pharmacies)

The hospital pharmacies segment is projected to witness robust growth and increase acinetobacter pneumonia therapeutics market share by the end of the forecast period. The segment’s growth is attributed to the large footfall of patients and its role in providing antibiotics and treatment for bacterial pneumonia. The segment is a major distribution channel for critically ill patients, as most severe cases occur in hospital settings; hence, the demand for effective treatment is concentrated at hospital pharmacies. Hospital pharmacies stock oral and parenteral antibiotics for bacterial pneumonia care, boosting the market’s growth as major distributors send their antibiotic stocks to the pharmacies due to increasing sales.

Our in-depth analysis of the Acinetobacter pneumonia therapeutics market includes the following segments: 

Route of Administration

  • Parenteral
  • Oral
  • Inhalation

Distribution Channel

  • Hospital Pharmacies
  • Retail Pharmacies
  • Online Pharmacies

Drug Class

  • Cephalosporins
  • Fluoroquinolone
  • Glycylcycline
  • Carbapenem
  • B-lactam antibiotics
  • Sulbactam
  • Aminoglycoside
  • Polymyxins
  • Tetracycline
  • Sulfonamide
  • Other drug classes

Age Group

  • Geriatric
  • Adult
  • Pediatric

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Acinetobacter Pneumonia Therapeutics Industry - Regional Synopsis

North America Market Analysis

North America in acinetobacter pneumonia therapeutics market is set to capture over 46.1% revenue share by 2037. The market’s growth is attributed to robust healthcare infrastructure in the region and an increasing diagnosis of Acinetobacter pneumonia cases. The market also benefits from a robust regulatory ecosystem that facilitates clinical trials and approvals of new antibiotic formulations to treat bacterial pneumonia. The presence of leading pharmaceutical companies and research institutes in North America plays a role in bolstering the market’s growth.

The U.S. holds the largest acinetobacter pneumonia therapeutics market share in North America. The market’s growth in the country is attributed to increasing diagnosis of bacterial pneumonia cases and the demands for novel solutions to manage infection. In December 2020, the morbidity and mortality weekly report by the Centers for Disease Control and Prevention stated an increase in hospital acquired carbapenem resistant Acinetobacter baumannii infection during a surge in COVID-19. There’s a growing focus in the country for early vaccination to generate an immune response before exposure to Acinetobacter baumannii.

Additionally, a robust healthcare system in the country facilitates key players to invest in research for antibiotic formulations for Acinetobacter pneumonia. For instance, in March 2021, the Department of Veteran Affairs (VA) launched the National Organization for NV-HAP Prevention (NOHAP) as an organized effort to assist in the prevention of hospital acquired pneumonia in hospitals across U.S.

Canada is poised to increase its revenue share in North America during the forecast period. The market’s growth is attributed to increased government investments in healthcare and drug research. For instance, in December 2023, the government of Canada announced the creation of the Canadian Drug Agency to make the drug system more sustainable and improve access of citizens to prescription drugs. Additionally, a robust ecosystem favorable to research is boosting the market’s growth. For instance, in May 2023, researchers from Hamilton University leveraged artificial intelligence (AI) to find treatment for a bacteria superbug.

APAC Market Analysis

The Asia Pacific acinetobacter pneumonia therapeutics market is poised to register the fastest growth by the end of the forecast period. The acinetobacter pneumonia therapeutics market growth is attributed to the rising prevalence of hospital acquired pneumonia (HAP) and ventilator-acquired pneumonia (VAP). For instance, in 2022, a study published in Science Direct assessed the factors predicting non-ventilated hospital-acquired pneumonia and found HAP results in almost 20% infections in hospitals, with more than two-thirds of patients not using mechanical ventilation. Additionally, the report indicated incidences of non-ventilated hospital acquired pneumonia (NVHAP) increasing and are associated with higher mortality rates.

China is leading the acinetobacter pneumonia therapeutics market share in Asia Pacific owing to rising awareness on combating the threat of multi drug resistant-Acinetobacter strains. Approval of new novelty therapeutics is set to boost the market’s continued growth in the country. In January 2019, a study published in the National Library of Medicine that reported a clinical HAP survey in 13 large hospitals in China reported a 1.4% incidence of HAP in ICUs, 15.3% in RICUs, and 0.9% in general wards. The percentage is likely to increase by the end of the forecast period owing to an aging population and longer hospital stays, increasing susceptibility to Acinetobacter baumannii.

 The demand for advanced therapeutics is rising in the country, and key market players are positioned to cater to demands. For instance, in May 2024, Zai Lab and Innoviva Specialty Therapeutics announced approval by China’s National Medical Products Administration (NMPA) for the new drug application for Xacduro.

India is projected to increase acinetobacter pneumonia therapeutics market share in Asia Pacific with a rapid growth curve by the end of the forecast period. The large-population in the country also increases footfalls in hospitals and other specialty clinics. The percentage of patients requiring ICU visits also increases due to the large population. This increases the percentage of patients vulnerable to various cases of hospital acquired pneumonia.

The government efforts in ramping up research to combat antimicrobial resistance creates new opportunities for pharmaceutical companies to develop novel therapeutics. For instance, in September 2023, Orchid Pharma, a subsidiary of Dhanuka Labs, announced that it had gained a sublicense to manufacture cefiderocol.

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Acinetobacter Pneumonia Therapeutics Market size
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Companies Dominating the Acinetobacter Pneumonia Therapeutics Landscape

    The global Acinetobacter pneumonia therapeutics market is positioned to witness a profitable growth curve during the forecast period. Key market players are investing in improving their distribution channels, research on multi drug resistant bacteria, clinical trials and drug approvals to treat bacterial pneumonia. Additionally, global players are partnering with local players to gain access to niche markets and improve revenue shares. Countries such as China, India, Japan, South Korea, and Australia are investing in their healthcare sector and increasing awareness on Acinetobacter baumannii infections which plays a critical role in the acinetobacter pneumonia therapeutics market’s growth.

    Here are some key players in the acinetobacter pneumonia therapeutics market:

    • Shionogi Inc.
      • Company Overview 
      • Business Strategy 
      • Key Product Offerings 
      • Financial Performance 
      • Key Performance Indicators 
      • Risk Analysis 
      • Recent Development 
      • Regional Presence 
      • SWOT Analysis 
    • AstraZeneca PLC
    • Pfizer Inc.
    • Sanofi
    • Bayer AG
    • Merck & Co., Ltd.
    • GlaxoSmithKline PLC
    • Novartis AG
    • Zimmer Biomet

In the News

  • In August 2024, the Galien Foundation announced the 2024 Prix Galien USA nominees for the best biotechnology product, best pharmaceutical product, and best product for rare/orphan diseases and Xacduro, an FDA approved drug for Acinetobacter pneumonia care, was nominated.
  • In May 2023, Innoviva Specialty Therapeutics announced the FDA approval for Xacduro for intravenous use for hospital-acquired bacterial pneumonia and ventilator-associated bacterial pneumonia.
  • In October 2022, Eagle Pharmaceuticals announced the FDA acceptance of the investigational drug application CALO2, a novel anti-virulence agent for the treatment of severe community acquired bacterial pneumonia.

Author Credits:  Radhika Pawar


  • Report ID: 6546
  • Published Date: Oct 11, 2024
  • Report Format: PDF, PPT

Frequently Asked Questions (FAQ)

The global acinetobacter pneumonia therapeutics market attained USD 496.9 million in 2024 and is poised to register a profitable CAGR of 6.4% during the forecast period, i.e., 2025-2037.

The global acinetobacter pneumonia therapeutics market registered a profitable valuation of USD 496.9 million in 2024 and is projected to attain a valuation of USD 1.1 billion by 2037 with a CAGR if 6.4% during the forecast period, i.e., 2025-2037.

The major players in the market are Shionogi Inc., AstraZeneca PLC, Pfizer Inc, Sanofi, Bayer AG, Merck & Co., Ltd., GlaxoSmithKline PLC, Novartis AG, Zimmer Biomet, and others.

The AC segment is poised to dominate the revenue share with a 51.6% market share during the forecast period. The segment's growth is attributed to its compatibility with existing infrastructure and increasing adoption due to its cost-efficiency in power protection systems. The parenteral segment dominated the market share in 2024 with a whooping 73.5% revenue share. The segment's growth is owed to large-scale application in severe cases of hospital acquired pneumonia.

North America is poised to register the highest market share in the global market with a revenue share of 46.1% by 2037. The growth of the market in the region is attributed to a robust healthcare infrastructure and regulatory ecosystem facilitating research on multi drug resistant bacteria.
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